[HTML][HTML] Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer
A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …
[HTML][HTML] Non-Alcoholic Fatty Liver Disease or Type 2 Diabetes Mellitus—The Chicken or the Egg Dilemma
M Kosmalski, A Śliwińska, J Drzewoski - Biomedicines, 2023 - mdpi.com
In clinical practice, we often deal with patients who suffer from non-alcoholic fatty liver
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …
Evaluation of flavonoids from banana pseudostem and flower (quercetin and catechin) as potent inhibitors of α-glucosidase: An in silico perspective
The amelioration of postprandial hyperglycemia in diabetic conditions could be
accomplished by the inhibition of α-glucosidases, a set of intestinal carbohydrate digestive …
accomplished by the inhibition of α-glucosidases, a set of intestinal carbohydrate digestive …
[HTML][HTML] Discovery of novel coumarin derivatives as potential dual inhibitors against α-glucosidase and α-amylase for the management of post-prandial hyperglycemia …
Coumarin derivatives are proven for their therapeutic uses in several human diseases and
disorders such as inflammation, neurodegenerative disorders, cancer, fertility, and microbial …
disorders such as inflammation, neurodegenerative disorders, cancer, fertility, and microbial …
Metabolites of gut microbiota and possible implication in development of diabetes mellitus
Diabetes mellitus is characterized by having a disorder of glucose metabolism. The types of
diabetes mellitus include type 1 diabetes mellitus, type 2 diabetes mellitus, gestational …
diabetes mellitus include type 1 diabetes mellitus, type 2 diabetes mellitus, gestational …
[HTML][HTML] Identification of the shared gene signatures and biological mechanism in type 2 diabetes and pancreatic cancer
Y Hu, N Zeng, Y Ge, D Wang, X Qin, W Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The relationship between pancreatic cancer (PC) and type 2 diabetes mellitus
(T2DM) has long been widely recognized, but the interaction mechanisms are still unknown …
(T2DM) has long been widely recognized, but the interaction mechanisms are still unknown …
Targeting pancreatic β cells for diabetes treatment
Insulin is a life-saving drug for patients with type 1 diabetes; however, even today, no
pharmacotherapy can prevent the loss or dysfunction of pancreatic insulin-producing β cells …
pharmacotherapy can prevent the loss or dysfunction of pancreatic insulin-producing β cells …
[HTML][HTML] Interplay among the oral microbiome, oral cavity conditions, the host immune response, diabetes mellitus, and its associated-risk factors—An overview
This comprehensive review of the literature aimed to investigate the interplay between the
oral microbiome, oral cavity conditions, and host immune response in Diabetes mellitus …
oral microbiome, oral cavity conditions, and host immune response in Diabetes mellitus …
[HTML][HTML] Multiprotein inhibitory effect of dietary polyphenol rutin from whole green jackfruit flour targeting different stages of diabetes mellitus: Defining a bio …
The anti-diabetic potential of whole unripe jackfruit (peel with pulp, flake, and seed) was
investigated using inhibitory assays for α-glucosidase, α-amylase, aldose reductase, and …
investigated using inhibitory assays for α-glucosidase, α-amylase, aldose reductase, and …
Dysfunctions, molecular mechanisms, and therapeutic strategies of pancreatic β-cells in diabetes
MK Prasad, S Mohandas, KM Ramkumar - Apoptosis, 2023 - Springer
Pancreatic beta-cell death has been established as a critical mediator in the progression of
type 1 and type 2 diabetes mellitus. Beta-cell death is associated with exacerbating …
type 1 and type 2 diabetes mellitus. Beta-cell death is associated with exacerbating …