Multiprotein inhibitory effect of dietary polyphenol rutin from whole green jackfruit flour targeting different stages of diabetes mellitus: defining a bio-computational …

T Maradesha, SM Patil, B Phanindra, RR Achar… - Separations, 2022 - mdpi.com
The anti-diabetic potential of whole unripe jackfruit (peel with pulp, flake, and seed) was
investigated using inhibitory assays for α-glucosidase, α-amylase, aldose reductase, and …

Association of serum magnesium with insulin resistance and type 2 diabetes among adults in China

W Li, Y Jiao, L Wang, S Wang, L Hao, Z Wang, H Wang… - Nutrients, 2022 - mdpi.com
Magnesium is an essential mineral for the human body and a cofactor or activator for more
than 300 enzymatic reactions, including blood glucose control and insulin release. Diabetes …

How curcumin targets inflammatory mediators in diabetes: therapeutic insights and possible solutions

Y Hussain, H Khan, G Alotaibi, F Khan, W Alam… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a multifactorial chronic metabolic disorder, characterized by altered
metabolism of macro-nutrients, such as fats, proteins, and carbohydrates. Diabetic …

The predicted mechanisms and evidence of probiotics on type 2 diabetes mellitus (T2DM)

O Bajinka, K Sylvain Dovi, L Simbilyabo… - … of Physiology and …, 2023 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a serious endocrine and metabolic disease that is highly
prevalent and causes high mortality and morbidity rates worldwide. This review aims to …

Association of non-Insulin-Based insulin resistance indices with risk of incident prediabetes and diabetes in a Chinese rural population: a 12-year prospective study

X Li, Y Xue, Y Dang, W Liu, Q Wang… - … and Obesity: Targets …, 2022 - Taylor & Francis
Objective Three non-insulin-based insulin resistance (IR) indices, ie, triglyceride-glucose
(TyG) index, triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, and …

Diabetes mellitus and the risk of ovarian cancer: a systematic review and meta-analysis of cohort and case–control studies

L Wang, L Zhong, B Xu, M Chen, H Huang - BMJ open, 2020 - bmjopen.bmj.com
Objective Emerging evidence from observational studies (cohort and case–control studies)
suggests that a history of diabetes mellitus (DM) has been linked to increased risk of ovarian …

Early insulin resistance, type 2 diabetes, and treatment options in childhood

N Polidori, F Mainieri, F Chiarelli, A Mohn… - Hormone research in …, 2022 - karger.com
Abstract Background: Type 2 diabetes (T2D) represents just the tip of the iceberg of the
complex metabolic alterations associated with obesity and other clinical conditions …

Fenofibrate alleviates insulin resistance by reducing tissue inflammation in obese ovariectomized mice

J Lee, S Jeon, M Lee, M Yoon - Nutrition & Diabetes, 2023 - nature.com
Background Fenofibrate is a hypolipidemic peroxisome proliferator-activated receptor α
(PPARα) agonist used clinically to reduce hypercholesterolemia and hypertriglyceridemia …

Sesquiterpene glycoside isolated from loquat leaf targets gut microbiota to prevent type 2 diabetes mellitus in db/db mice

R Wu, L Zhou, Y Chen, X Ding, Y Liu, B Tong, H Lv… - Food & Function, 2022 - pubs.rsc.org
According to ancient records, loquat leaf has been used as both a food and medicine in
China for thousands of years. Sesquiterpene glycosides from loquat leaf have achieved …

Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring

Q Yang, Y Mao, J Wang, H Yu… - Human & …, 2022 - journals.sagepub.com
Lipid metabolism is an important biochemical process in the body. Recent studies have
found that environmental endocrine disruptors play an important role in the regulation of …