Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3‐L1 preadipocytes

Z Yao, J Meng, J Long, L Li, W Qiu, C Li… - FEBS Open …, 2023 - Wiley Online Library
Type 2 diabetes (T2DM) is characterized by insulin secretion deficiencies and systemic
insulin resistance (IR) in adipose tissue, skeletal muscle, and the liver. Although the …

Foot Exercise to Overcome Type 2 Diabetes Mellitus: A literature Review

A Zakiudin, G Irianto, A Badrujamaludin… - … Journal of Nursing …, 2022 - journal.qqrcenter.com
Prediction in 2030, the number of deaths due to Diabetes Mellitus (DM) will increase and
become the seventh cause of death. The role of patients in managing DM is vital because …

Study on Optimal Extraction and Hypoglycemic Effect of Quercetin

L Zhang, M Pan, T Li, Z Jin, Z Liu, Q Liu… - Evidence‐Based …, 2023 - Wiley Online Library
Quercetin was extracted from Portulaca oleracea L. through biphasic acid hydrolysis to
investigate its potential as a suppressor of dipeptidyl peptidase IV (DPP‐IV) and its …

[HTML][HTML] Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass

B Serra-Navarro, R Fernandez-Ruiz… - Molecular …, 2021 - Elsevier
Objective Early postnatal life is a critical period for the establishment of the functional β-cell
mass that will sustain whole-body glucose homeostasis during the lifetime. β cells are …

[HTML][HTML] The antioxidant, antidiabetic, and antihyperlipidemic effects of the polyphenolic extract from Salvia blancoana subsp. mesatlantica on induced diabetes in …

S Maache, H Laaroussi, N Soulo, G Nouioura… - Bioresources and …, 2024 - Springer
Currently, several studies have demonstrated the benefits of medicinal plants in managing
type 2 diabetes. In this work, we evaluated the beneficial effects of the polyphenolic extract …

[HTML][HTML] Effects of ginseng peptides on the hypoglycemic activity and gut microbiota of a type 2 diabetes mellitus mice model

C Han, X Kong, X Xia, X Huang, Z Mao, J Han… - Journal of Functional …, 2023 - Elsevier
Abstract Ginseng peptide (GP)(100, 200, 400 mg/kg bw) lowered blood glucose levels,
explored the relationship between GP and gut microbiota-based hypoglycemic effects. GP …

Stereoselective Synthesis of Highly Functionalized Aminobenzothiazole-Fused Spirooxindole Derivatives: in silico and in vitro Anti-Diabetic Studies

N Nivetha, SM Patil, R Ramu, S Sreenivasa… - …, 2023 - thieme-connect.com
A series of highly functionalized spirooxindole pyrrolizidine/pyrrolothiazole derivatives have
been synthesized by the three-component 1, 3-dipolar cycloaddition reaction of …

Evaluating insulindysregulation in horses: A two-step insulin-tolerance test using porcine zinc insulin

AJ Grob, J Delarocque, K Feige, T Warnken - The Veterinary Journal, 2024 - Elsevier
In insulin dysregulation, hyperinsulinemia (HI) can be accompanied by peripheral insulin
resistance (IR) in horses, which can be diagnosed with an insulin-tolerance test (ITT). The …

Guidelines for cellular and animal models of insulin resistance in type 2 diabetes

Y Wen, Y Ouyang, Y Liu, R Zhong, Q Huang, C Zhao - eFood, 2022 - Wiley Online Library
As a lifelong chronic metabolic disease, there is no effective method to completely eradicate
diabetes. In the search for effective treatments, disease models are important as a means of …

Insulin: produksi, jenis, analisis, dan rute pemberian

D Hardianto - Jurnal Bioteknologi dan Biosains Indonesia, 2021 - ejournal.brin.go.id
Diabetes mellitus (DM) is a metabolic disorder disease characterized by hyperglycemia due
to insulin deficiency, insulin resistance, or both. In 2019, people with DM reached 463 …