[HTML][HTML] A revealing review of mesenchymal stem cells therapy, clinical perspectives and Modification strategies

P Saeedi, R Halabian, AAI Fooladi - Stem cell investigation, 2019 - ncbi.nlm.nih.gov
Multipotent mesenchymal stem cells (MSCs) have been considerably inspected as effective
tool for cell-based therapy of inflammatory, immune-mediated, and degenerative diseases …

Role of mesenchymal stem cells in bone regenerative medicine: what is the evidence?

A Oryan, A Kamali, A Moshiri… - Cells Tissues …, 2017 - karger.com
Healing and regeneration of bone injuries, particularly those that are associated with large
bone defects, are a complicated process. There is growing interest in the application of …

Tissue repair and regeneration with endogenous stem cells

H Xia, X Li, W Gao, X Fu, RH Fang, L Zhang… - Nature Reviews …, 2018 - nature.com
In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics …

The potential of human umbilical cord-derived mesenchymal stem cells as a novel cellular therapy for multiple sclerosis

JF Li, DJ Zhang, T Geng, L Chen, H Huang… - Cell …, 2014 - journals.sagepub.com
Multiple sclerosis (MS) is a complex disease of neurological disability, affecting more than
300 out of every 1 million people in the world. The purpose of the study was to evaluate the …

An update for mesenchymal stem cell therapy in lupus nephritis

W Li, W Chen, L Sun - Kidney Diseases, 2021 - karger.com
Background: Lupus nephritis (LN) is the most severe organ manifestations of systemic lupus
erythematosus (SLE). Although increased knowledge of the disease pathogenesis has …

The immunomodulatory effects of mesenchymal stromal cell‐based therapy in human and animal models of systemic lupus erythematosus

F Radmanesh, M Mahmoudi, E Yazdanpanah… - IUBMB …, 2020 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune inflammatory
disease with no absolute cure. Although the exact etiopathogenesis of SLE is still enigmatic …

Modulation of immunoregulatory properties of mesenchymal stromal cells by toll‐like receptors: Potential applications on GVHD

B Sangiorgi, RA Panepucci - Stem cells international, 2016 - Wiley Online Library
In the last decade, the immunomodulatory properties of mesenchymal stromal cells (MSCs)
have attracted a lot of attention, due to their potential applicability in the treatment of graft …

Umbilical cord mesenchymal stem cells in neurological disorders: A clinical study.

X Miao, X Wu, W Shi - Indian Journal of Biochemistry & Biophysics, 2015 - europepmc.org
We investigated the intrathecally administrated unbilical cord mesenchymal stem cells (UC-
MSCs) by lumbar puncture and assessed the technical difficulties and effects in various …

Two sides of the same coin: stem cells in cancer and regenerative medicine

M Ilmer, J Vykoukal, AR Boiles, M Coleman… - The FASEB …, 2014 - Wiley Online Library
Multipotent stromal cells (MSCs) derived from bone marrow, adipose tissue, cord blood, and
other origins have recently received much attention as potential therapeutic agents with …

An injectable extracellular matrix for the reconstruction of epidural fat and the prevention of epidural fibrosis

CY Lin, TY Liu, MH Chen, JS Sun… - Biomedical materials, 2016 - iopscience.iop.org
Extensive epidural fibrosis is a common complication following spinal surgery and can
cause pain and limited mobility. In the present study, a novel biomimetic approach was …