[引用][C] Characterization of mAb6-9-1 monoclonal antibody against hemagglutinin of avian influenza virus H5N1 and its engineered derivative, single-chain variable …
R Sawicka, P Siedlecki, B Kalenik… - Acta Biochimica …, 2017 - ojs.ptbioch.edu.pl
Hemagglutinin (HA), as a major surface antigen of influenza virus, is widely used as a target
for production of neutralizing antibodies. Monoclonal antibody, mAb6-9-1, directed against …
for production of neutralizing antibodies. Monoclonal antibody, mAb6-9-1, directed against …
Expression of soluble human Neonatal Fc-receptor (FcRn) in Escherichia coli through modification of growth environment
Abstract Neonatal Fc-receptor (FcRn) with its affinity to immunoglobulin G (IgG) has been the
subject of many pharmacokinetic studies in the past century. This protein is well known for its …
subject of many pharmacokinetic studies in the past century. This protein is well known for its …
单链抗体的原核可溶性表达及临床应用
周勇军, 姚于勤, 杨金亮, 王明蓉 - 华西医学, 2012 - cqvip.com
利用原核表达系统表达外源基因来获取大量有活性的蛋白质是目前最常用且经济的方法.
由于原核表达系统的自身特点, 单链抗体的表达往往以无活性的包涵体存在 …
由于原核表达系统的自身特点, 单链抗体的表达往往以无活性的包涵体存在 …
一种新型结缔组织生长因子人源单链抗体的可溶性表达以及分离纯化
范小波, 苟丽霞, 刘昭, 沈子龙, 刘乃丰, 吴国球… - 东南大学学报: 医学 …, 2010 - cqvip.com
目的: 研究单链抗体(scFv) 在不同载体和菌株中的表达以及表达产物的免疫学活性评价. 方法:
将人源化单链抗体的基因通过酶切, 连接等生物技术的方法克隆到pET28a, pET32a 和pET-EI …
将人源化单链抗体的基因通过酶切, 连接等生物技术的方法克隆到pET28a, pET32a 和pET-EI …
In vivo diversification of target genomic sites using processive T7 RNA polymerase-base deaminase fusions blocked by RNA-guided dCas9
Diversification of specific DNA segments typically involve in vitro generation of large
sequence libraries and their introduction in cells for selection. Alternative in vivo …
sequence libraries and their introduction in cells for selection. Alternative in vivo …
B-pinene synthesis in synechococcus sp. pcc 7002 cyanobacteria: metabolic engineering for high-density biofuel applications
R Carr - 2017 - minds.wisconsin.edu
In light of escalating concern over global climate change and the declining availability of non-
renewable fossil fuels, a significant body of research has accumulated which explores …
renewable fossil fuels, a significant body of research has accumulated which explores …
[图书][B] Estudi de la via d'agregació de tres proteïnes implicades en diferents malalties conformacionals humanes: scFv-h3D6 com agent terapèutic per a la malaltia d' …
M Marin Argany - 2014 - ddd.uab.cat
Aquesta Tesi Doctoral es centra en l'estudi molecular de tres proteïnes relacionades amb
malalties conformacionals humanes, o Amiloïdosis. Mitjançant tècniques …
malalties conformacionals humanes, o Amiloïdosis. Mitjançant tècniques …
Inhibition of disulfide reductases as a therapeutic strategy
NO Kaakoush, GL Mendz - Current Enzyme Inhibition, 2009 - ingentaconnect.com
Disulfide reductases are involved in many functions in the cell, in particular, maintaining the
intracellular redox balance. Many classes of these enzymes exist, and their inhibition has …
intracellular redox balance. Many classes of these enzymes exist, and their inhibition has …
Functional improvement of human cardiotrophin 1 produced in tobacco chloroplasts by co-expression with plastid thioredoxin m
M Ancín Rípodas, R Sanz Barrio… - Plants, 2020, 9 …, 2020 - academica-e.unavarra.es
Human cardiotrophin 1 (CT1), a cytokine with excellent therapeutic potential, was previously
expressed in tobacco chloroplasts. However, the growth conditions required to reach the …
expressed in tobacco chloroplasts. However, the growth conditions required to reach the …
Production and purification of monomeric recombinant peptide aptamers: requirements for efficient intracellular uptake and target inhibition
C Borghouts, A Weiss - Peptides as Drugs: Discovery and …, 2009 - Wiley Online Library
Special classes of molecules are required to interfere with specific protein interactions. The
protein surfaces that mediate the interactions are usually large, lack well-defined binding …
protein surfaces that mediate the interactions are usually large, lack well-defined binding …