A new series of 12 N4-substituted isatin-3-thiosemicarbazones 2a-l has been synthesized,
characterized and screened for in vitro cytotoxic, phytotoxic and urease inhibitory effects. All …

A pentadentate phenol‐containing ligand (H3L) with N2O3 donor atoms yields NiII2 (1),
NiII4 (2), CuII2 (3) and CuII4 (4) complexes, which have been structurally characterized by X …

Maturation of urease involves post-translational insertion of nickel ions to form an active site
with a carbamylated lysine ligand and is assisted by urease accessory proteins UreD, UreE …

Urease uses a cluster of two NiII ions to activate a water molecule for urea hydrolysis. The
key to this unsurpassed enzyme is a change in the conformation of a flexible structural motif …

Since the urease enzyme creates gastric cancer, peptic ulcer, hepatic coma, and urinary
stones in millions of people worldwide, it is essential to find strong inhibitors to help patients …

Urease is the most efficient enzyme known to date, and catalyzes the hydrolysis of urea
using two Ni (II) ions in the active site. Urease is a virulence factor in several human …

The inhibition of urease enzyme is very important as it plays a key role in the treatment of
several urinary and gastrointestinal tract infections. This enzyme provides a suitable …

We performed a multi-step analysis of the inhibition of jack bean urease by Hg2+ ions that
included residual activity measurements after incubation of the enzyme with the metal ion …

ABSTRACT Microbially Induced Calcite Precipitation (MICP, or biocalcification) is a
biochemical process governed by microbial activity to induce the precipitation of calcite …

Intake of water contaminated with lead (Pb 2+) and mercury (Hg 2+) ions leads to various
toxic effects and health issues. In this context, an amperometric urease inhibition-based …