Abstract Helicobacter pylori UreF (Hp UreF) is involved in the insertion of Ni 2+ in the urease
active site. The recombinant protein in solution is a dimer characterized by an extensive α …

To provide theoretical guidance for better healing ability of microbial self-healing concrete,
the mechanism of urea decomposition catalyzed by Sporosarcina pasteurii urease in …

Urease plays a significant role in the pathogenesis of several diseases and also has
practical implications in other fields, such as agriculture or chemical analysis. Among the …

Two new dinucleating pyrazole ligands HL1 and HL2 bearing appended 1, 4-diisopropyl-1,
4, 7-triazacyclononane (iPr2TACN) side arms in the 3-and 5-positions have been …

The fertilizer additive products Nutrisphere and Avail use a coating of maleic–itaconic acid
copolymer and have been marketed worldwide. It is claimed that the copolymer (trade name …

Synthesis of quinoline analogs and their urease inhibitory activities with reference to the
standard drug, thiourea (IC 50= 21.86±0.40 µM) are presented in this study. The inhibitory …

A pharmacophore model was developed based on three structurally diverse urease
inhibitors by using the GASP program. This model comprises the positions and tolerance for …

Urease, the most efficient enzyme so far discovered, depends on the presence of nickel ions
in the catalytic site for its activity. The transformation of inactive apo-urease into active holo …

An inhibiting effect of fresh garlic extract (GE) on jack bean urease has been investigated in
order to elucidate the kinetics and mechanism of inhibition. The system: jack bean urease …

A series of seventeen N4-substituted 5-nitroisatin-3-thiosemicarbazones 2a-2q has been
synthesized and screened for in vitro urease inhibitory activities. Compounds 2a-2d, 2g, 2i …