The malarial blood transcriptome: translational applications

C Dunican, C Andradi-Brown, S Ebmeier… - Biochemical Society …, 2024 - portlandpress.com
The blood transcriptome of malaria patients has been used extensively to elucidate the
pathophysiological mechanisms and host immune responses to disease, identify candidate …

Host-Derived Extracellular Vesicles in Blood and Tissue Human Protozoan Infections

N Tiberti, SS Longoni, V Combes, C Piubelli - Microorganisms, 2023 - mdpi.com
Blood and tissue protozoan infections are responsible for an enormous burden in tropical
and subtropical regions, even though they can also affect people living in high-income …

Use of a health worker-targeted smartphone app to support quality malaria RDT implementation in Busia County, Kenya: A feasibility and acceptability study

M Skjefte, S Cooper, S Poyer, C Lourenço… - Plos one, 2024 - journals.plos.org
Malaria rapid diagnostic tests (mRDTs) are an essential diagnostic tool in low-resource
settings; however, administration and interpretation errors reduce their effectiveness …

Evaluation of Malaria Rapid Diagnostic Test Performance and pfhrp2 Deletion in Tanzania School Surveys, 2017.

B Ngasala, F Chacky, A Mohamed… - The American Journal …, 2024 - europepmc.org
As part of malaria nationwide monitoring and evaluation initiatives, there is an increasing
trend of incorporating malaria rapid diagnostic tests (mRDTs) in surveys conducted within …

Widespread pfhrp2/3 deletions and HRP2-based false-negative results in southern Ethiopia

B Mekonen, S Dugassa, SM Feleke, B Dufera, B Gidisa… - Malaria Journal, 2024 - Springer
Abstract Background Rapid diagnostic tests (RDTs) play a significant role in expanding case
management in peripheral healthcare systems. Histidine-rich protein-2 (HRP2) antigen …

The Laboratory Diagnosis of Malaria: A Focus on the Diagnostic Assays in Non-Endemic Areas

A Calderaro, G Piccolo, C Chezzi - International Journal of Molecular …, 2024 - mdpi.com
Even if malaria is rare in Europe, it is a medical emergency and programs for its control
should ensure both an early diagnosis and a prompt treatment within 24–48 h from the onset …

Conducting active screening for human African trypanosomiasis with rapid diagnostic tests: The Guinean experience (2016–2021)

O Camara, JW Kaboré, A Soumah… - PLOS Neglected …, 2024 - journals.plos.org
Strategies to detect Human African Trypanosomiasis (HAT) cases rely on serological
screening of populations exposed to trypanosomes. In Guinea, mass medical screening …

Identification and management of co-infections in people with malaria

AJ Cunnington, A Abbara, FK Bawa, J Achan - bmj, 2024 - bmj.com
A 16 year old Ugandan girl is brought to the emergency department with a three day history
of fever, headache, cough, and myalgia. She has had several episodes of malaria in the …

Evaluation of the Performance of Rapid Diagnostic Tests for Malaria Diagnosis and Mapping of Different Plasmodium Species in Mali

P Dembélé, M Cissoko, AZ Diarra, L Doumbia… - International Journal of …, 2024 - mdpi.com
Background: The first-line diagnosis of malaria in Mali is based on the use of rapid
diagnostic tests (RDT) that detect the Histidin Rich Protein 2 (HRP2) antigen specific to …

Comparative Diagnostic Performance of Microscopy, SD‐Bioline Rapid Diagnostic Test, and Polymerase Chain Reaction in the Detection of Malaria Infection among …

B Ngemani Obase, E Livo Forgu… - Journal of Tropical …, 2023 - Wiley Online Library
Introduction. Malaria during pregnancy is a major cause of morbidity and mortality in sub‐
Saharan Africa. Microcopy and rapid diagnostic test (RDT) recommended by the World …