Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications

PK Mukherjee, T Efferth, B Das, A Kar, S Ghosh… - Phytomedicine, 2022 - Elsevier
Background The worldwide corona virus disease outbreak, generally known as COVID-19
pandemic outbreak resulted in a major health crisis globally. The morbidity and transmission …

Herbal therapy for the treatment of acetaminophen-associated liver injury: recent advances and future perspectives

L Chang, D Xu, J Zhu, G Ge, X Kong… - Frontiers in …, 2020 - frontiersin.org
Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury
worldwide, and mitochondrial oxidative stress is considered the major event responsible for …

[HTML][HTML] Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity by targeting Nrf2 and NEK7-NLRP3 signaling pathway

Y Yao, R Li, D Liu, L Long, N He - Ecotoxicology and Environmental Safety, 2022 - Elsevier
Rosmarinic acid (RA) is a natural polyphenol with various biological activities, such as anti-
oxidative, anti-fibrotic, and hepatoprotective properties. The objective of this study was to …

[HTML][HTML] Effects of arsenic and heavy metals on metabolic pathways in cells of human origin: similarities and differences

K Fatema, SS Shoily, T Ahsan, Z Haidar, AF Sumit… - Toxicology reports, 2021 - Elsevier
Various anthropogenic and natural events over the years have gradually increased human
exposure to various heavy metals. Several of these heavy metals including cadmium …

The late-stage protective effect of Mito-TEMPO against acetaminophen-induced hepatotoxicity in mouse and three-dimensional cell culture models

M Abdullah-Al-Shoeb, K Sasaki, S Kikutani, N Namba… - Antioxidants, 2020 - mdpi.com
An overdose of acetaminophen (APAP), the most common cause of acute liver injury,
induces oxidative stress that subsequently causes mitochondrial impairment and hepatic …

Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review

N Tavvabi-Kashani, M Hasanpour, VB Rahimi… - Toxicon, 2024 - Elsevier
The active biological phytochemicals, crucial compounds employed in creating hundreds of
medications, are derived from valuable and medicinally significant plants. These …

Angelica keiskei: A promising antioxidant and anticancer agent for Photothermal mediated drug delivery applications

AA Singh, N David, M Misra, BS Chun - Journal of Molecular Structure, 2024 - Elsevier
Abstracts Cancer remains one of the leading causes of mortality worldwide, necessitating
the continuous search for novel and effective therapeutic strategies. This work explored the …

Hepatoprotective effect of eugenol on acetaminophen-induced hepatotoxicity in HepG2 cells

INE Lister, CN Ginting, E Girsang… - Journal of Physics …, 2019 - iopscience.iop.org
Imbalance in liver metabolism lead to oxidative stress mainly caused by free radicals or
termed as reactive oxidative oxygen (ROS). Prolonged ROS exposure without proper …

The pharmacology activities of Angelica keiskei Koidzumi and its efficacy and safety in humans

I Wahyuni, DL Aulifa, AM Rosdianto, J Levita - Heliyon, 2024 - cell.com
Chronic exposure to elevated levels of pro-oxidant factors may cause structural failings at
the mitochondrial DNA level and alteration of antioxidant enzymes (glutathione peroxidase …

Hepatoprotective effects of four Brazilian savanna species on acetaminophen-induced hepatotoxicity in HepG2 cells

GS Ribeiro, DHN Martins, JVD Gomes, NW Davies… - Plants, 2023 - mdpi.com
We investigated four Cerrado plant species, ie, Cheiloclinium cognatum (Miers) AC Sm,
Guazuma ulmifolia Lam., Hancornia speciosa Gomes, and Hymenaea stigonocarpa Mart. ex …