How cortical circuits implement cortical computations: mouse visual cortex as a model
CM Niell, M Scanziani - Annual Review of Neuroscience, 2021 - annualreviews.org
The mouse, as a model organism to study the brain, gives us unprecedented experimental
access to the mammalian cerebral cortex. By determining the cortex's cellular composition …
access to the mammalian cerebral cortex. By determining the cortex's cellular composition …
Cerebral cortical folding, parcellation, and connectivity in humans, nonhuman primates, and mice
DC Van Essen, CJ Donahue… - Proceedings of the …, 2019 - National Acad Sciences
Advances in neuroimaging and neuroanatomy have yielded major insights concerning
fundamental principles of cortical organization and evolution, thus speaking to how well …
fundamental principles of cortical organization and evolution, thus speaking to how well …
[HTML][HTML] Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines
A subanesthetic dose of ketamine causes acute psychotomimetic symptoms and sustained
antidepressant effects. In prefrontal cortex, the prevailing disinhibition hypothesis posits that …
antidepressant effects. In prefrontal cortex, the prevailing disinhibition hypothesis posits that …
[HTML][HTML] Thalamic control of cortical dynamics in a model of flexible motor sequencing
The neural mechanisms that generate an extensible library of motor motifs and flexibly string
them into arbitrary sequences are unclear. We developed a model in which inhibitory basal …
them into arbitrary sequences are unclear. We developed a model in which inhibitory basal …
Principles of corticocortical communication: proposed schemes and design considerations
Nearly all brain functions involve routing neural activity among a distributed network of
areas. Understanding this routing requires more than a description of interareal anatomical …
areas. Understanding this routing requires more than a description of interareal anatomical …
[HTML][HTML] Enhancer viruses for combinatorial cell-subclass-specific labeling
Rapid cell type identification by new genomic single-cell analysis methods has not been met
with efficient experimental access to these cell types. To facilitate access to specific neural …
with efficient experimental access to these cell types. To facilitate access to specific neural …
The fractal brain: scale-invariance in structure and dynamics
The past 40 years have witnessed extensive research on fractal structure and scale-free
dynamics in the brain. Although considerable progress has been made, a comprehensive …
dynamics in the brain. Although considerable progress has been made, a comprehensive …
[HTML][HTML] Regional, layer, and cell-type-specific connectivity of the mouse default mode network
The evolutionarily conserved default mode network (DMN) is a distributed set of brain
regions coactivated during resting states that is vulnerable to brain disorders. How disease …
regions coactivated during resting states that is vulnerable to brain disorders. How disease …
Neural algorithms and circuits for motor planning
The brain plans and executes volitional movements. The underlying patterns of neural
population activity have been explored in the context of movements of the eyes, limbs …
population activity have been explored in the context of movements of the eyes, limbs …
[HTML][HTML] Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model
Y Chen, Z Hong, J Wang, K Liu, J Liu, J Lin, S Feng… - Cell, 2023 - cell.com
Parkinson's disease (PD) is a debilitating neurodegenerative disorder. Its symptoms are
typically treated with levodopa or dopamine receptor agonists, but its action lacks specificity …
typically treated with levodopa or dopamine receptor agonists, but its action lacks specificity …