[HTML][HTML] NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: molecular mechanisms and possible therapeutic approaches
Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular
defense mechanisms as well as physiological functions, and intracellular signaling …
defense mechanisms as well as physiological functions, and intracellular signaling …
[HTML][HTML] The role of antioxidants in the interplay between oxidative stress and senescence
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …
[HTML][HTML] Polyphenols journey through blood-brain barrier towards neuronal protection
I Figueira, G Garcia, RC Pimpão, AP Terrasso… - Scientific reports, 2017 - nature.com
Age-related complications such as neurodegenerative disorders are increasing and remain
cureless. The possibility of altering the progression or the development of these …
cureless. The possibility of altering the progression or the development of these …
COPD and stroke: are systemic inflammation and oxidative stress the missing links?
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation and loss of lung function, and is currently the third largest cause of death in the …
limitation and loss of lung function, and is currently the third largest cause of death in the …
A review on in vitro model of the blood-brain barrier (BBB) based on hCMEC/D3 cells
D Qi, H Lin, B Hu, Y Wei - Journal of Controlled Release, 2023 - Elsevier
The establishment of in vitro models of the BBB is significant for the evaluation of the
mechanism and permeability of drugs and their sustained-release formulations across the …
mechanism and permeability of drugs and their sustained-release formulations across the …
[HTML][HTML] Effects of natural polyphenols on oxidative stress-mediated blood-brain barrier dysfunction
Y Kim, AY Cho, HC Kim, D Ryu, SA Jo, YS Jung - antioxidants, 2022 - mdpi.com
The blood-brain barrier (BBB), which consists mainly of brain microvascular endothelial cells
and astrocytes connected by tight junctions (TJs) and adhesion molecules (AMs), maintains …
and astrocytes connected by tight junctions (TJs) and adhesion molecules (AMs), maintains …
[HTML][HTML] Cerebrovascular and neurological disorders: protective role of NRF2
Cellular defense mechanisms, intracellular signaling, and physiological functions are
regulated by electrophiles and reactive oxygen species (ROS). Recent works strongly …
regulated by electrophiles and reactive oxygen species (ROS). Recent works strongly …
[HTML][HTML] The antioxidant MitoQ protects against CSE-induced endothelial barrier injury and inflammation by inhibiting ROS and autophagy in human umbilical vein …
S Chen, Y Wang, H Zhang, R Chen, F Lv… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is a common disease characterized by
persistent airflow limitation. Pulmonary vascular endothelial barrier injury and inflammation …
persistent airflow limitation. Pulmonary vascular endothelial barrier injury and inflammation …
[HTML][HTML] Cerebrovascular and neurological dysfunction under the threat of COVID-19: is there a comorbid role for smoking and vaping?
The recently discovered novel coronavirus, SARS-CoV-2 (COVID-19 virus), has brought the
whole world to standstill with critical challenges, affecting both health and economic sectors …
whole world to standstill with critical challenges, affecting both health and economic sectors …
[HTML][HTML] The potential for natural antioxidant supplementation in the early stages of neurodegenerative disorders
F Oppedisano, J Maiuolo, M Gliozzi… - International journal of …, 2020 - mdpi.com
The neurodegenerative process is characterized by the progressive ultrastructural
alterations of selected classes of neurons accompanied by imbalanced cellular …
alterations of selected classes of neurons accompanied by imbalanced cellular …