▪ Abstract Alternative pre-mRNA splicing is a central mode of genetic regulation in higher
eukaryotes. Variability in splicing patterns is a major source of protein diversity from the …

▪ Abstract The cellular stress response is a universal mechanism of extraordinary
physiological/pathophysiological significance. It represents a defense reaction of cells to …

The best understood system for the transport of macromolecules between the cytoplasm and
the nucleus is the classical nuclear import pathway. In this pathway, a protein containing a …

Cells in the renal inner medulla are normally exposed to extraordinarily high levels of NaCl
and urea. The osmotic stress causes numerous perturbations because of the hypertonic …

First described 15 years ago as a cysteine-rich sequence that was common to a small group
of homeodomain transcription factors, the LIM domain is now recognized as a tandem zinc …

In yeast, the transcription factor Crz1 is dephosphorylated and translocates into the nucleus
in response to extracellular calcium. Here we show, using time-lapse microscopy, that Crz1 …

Glutathione, altruistic metabolite in fungi Page 2 Contents CONTRIBUTORS TO VOLUME
49 vii Glutathione, Altruistic Metabolite in Fungi Istvan Pocsi, Rolf A. Prade and Michel J …

Reversible posttranslational modifications on specific amino acid residues can efficiently
regulate protein functions. O-Phosphorylation is the prototype and analogue to the rapidly …

To understand the molecular events coupling between cell proliferation and differentiation
by elucidating genes essential for the process, we conducted a large scale gene expression …

Integrin-mediated adhesion to the extracellular matrix regulates the cellular response to
mitogens. Anchorage-dependent growth factor activation of the extracellular signal …