[HTML][HTML] Galectin-3 induces a pro-degradative/inflammatory gene signature in human chondrocytes, teaming up with galectin-1 in osteoarthritis pathogenesis
D Weinmann, K Schlangen, S André, S Schmidt… - Scientific Reports, 2016 - nature.com
Inflammatory chemo-and cytokines and matrix-degrading proteases underlie the
progression of osteoarthritis (OA). Aiming to define upstream regulators for these disease …
progression of osteoarthritis (OA). Aiming to define upstream regulators for these disease …
Galectin-3 is a key hepatoprotective molecule against the deleterious effect of cisplatin
Aims Evaluate the role of galectin-3 in the liver using an acute model of cisplatin-induced
toxicity. Material and methods Modified citrus pectin (MCP) treatment was used to inhibit …
toxicity. Material and methods Modified citrus pectin (MCP) treatment was used to inhibit …
Proteomic analysis of isolated membrane fractions from superinvasive cancer cells
The superinvasive phenotype exhibited by paclitaxel-selected variants of an in vitro invasive
clonal population of the human cancer cell line, MDA-MB-435S were examined using DIGE …
clonal population of the human cancer cell line, MDA-MB-435S were examined using DIGE …
Why anti-Bcl-2 clinical trials fail: a solution
Y Harazono, K Nakajima, A Raz - Cancer and Metastasis Reviews, 2014 - Springer
The alteration in expression of B cell lymphoma-2 (Bcl-2) family of protein members in
cancer is involved mainly in the regulation of apoptosis. Bcl-2 family proteins are currently …
cancer is involved mainly in the regulation of apoptosis. Bcl-2 family proteins are currently …
Transcriptomics-based characterization of the toxicity of ZnO nanoparticles against chronic myeloid leukemia cells
SA Alsagaby, R Vijayakumar… - International Journal …, 2020 - Taylor & Francis
Introduction Zinc oxide nanoparticles (ZnO NPs) have recently attracted attention as
potential anti-cancer agents. To the best of our knowledge, the toxicity of ZnO NPs against …
potential anti-cancer agents. To the best of our knowledge, the toxicity of ZnO NPs against …
The acid and neutral fractions of pectins isolated from ripe and overripe papayas differentially affect galectin-3 inhibition and colon cancer cell growth
L de Freitas Pedrosa, RG Lopes, JP Fabi - International Journal of …, 2020 - Elsevier
The water-soluble fractions of pectin extracted from the pulp of ripe papayas have already
been found to exert positive effects on cancer cell cultures. However, the mechanisms that …
been found to exert positive effects on cancer cell cultures. However, the mechanisms that …
[HTML][HTML] Endogenous galectin-9 suppresses apoptosis in human rheumatoid arthritis synovial fibroblasts
Abstract Galectin-9 (Gal9) has been postulated to have anti-inflammatory properties based
on the ability of exogenous Gal9 to induce apoptosis in synovial fibroblasts in animal models …
on the ability of exogenous Gal9 to induce apoptosis in synovial fibroblasts in animal models …
[HTML][HTML] Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration
C Margadant, I van den Bout, AL van Boxtel… - Journal of Biological …, 2012 - ASBMB
Introduction of the integrin β1-but not the β3-subunit in GE11 cells induces an epithelial-to-
mesenchymal-transition (EMT)-like phenomenon that is characterized by the loss of cell-cell …
mesenchymal-transition (EMT)-like phenomenon that is characterized by the loss of cell-cell …
Galectin-3 as a biomarker in breast neoplasms: Mechanisms and applications in patient care
Galectin-3 is a member of the lectin family encoded by the LGALS3 gene on chromosome
14. It is secreted by a wide range of immune cells and mammary tumor cells. Through its …
14. It is secreted by a wide range of immune cells and mammary tumor cells. Through its …
[HTML][HTML] Early hyperbaric oxygen treatment attenuates burn-induced neuroinflammation by inhibiting the galectin-3-dependent toll-like receptor-4 pathway in a rat …
ZS Wu, JJ Lo, SH Wu, CZ Wang, RF Chen… - International journal of …, 2018 - mdpi.com
Hyperbaric oxygen (HBO) treatment has been proven to decrease neuroinflammation in rats.
This study aimed to determine the potential mechanism underlying the anti-inflammatory …
This study aimed to determine the potential mechanism underlying the anti-inflammatory …