Validated computational models predict vagus nerve stimulation thresholds in preclinical animals and humans

ED Musselman, NA Pelot, WM Grill - Journal of Neural …, 2023 - iopscience.iop.org
Objective. We demonstrated how automated simulations to characterize electrical nerve
thresholds, a recently published open-source software for modeling stimulation of peripheral …

Non-invasive imaging of neural activity with magnetic detection electrical impedance tomography (MDEIT): a modelling study

K Mason, K Aristovich, D Holder - Physiological Measurement, 2023 - iopscience.iop.org
Objectives.(1) Develop a computational pipeline for three-dimensional fast neural magnetic
detection electrical impedance tomography (MDEIT),(2) determine whether constant current …

[HTML][HTML] Anatomical and functional organization of cardiac fibers in the porcine cervical vagus nerve allows spatially selective efferent neuromodulation

N Thompson, E Ravagli, S Mastitskaya, R Challita… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Cardiac disease progression reflects the dynamic interaction between adversely remodeled
neurohumoral control systems and an abnormal cardiac substrate. Vagal nerve stimulation …

Selective efferent vagal stimulation in heart failure

LC Booth, B Saseetharan, CN May… - Experimental …, 2023 - Wiley Online Library
Patients diagnosed with heart failure have high rates of mortality and morbidity. Based on
promising preclinical studies, vagal nerve stimulation has been trialled in these patients …

Noise-based correction for electrical impedance tomography

K Mason, F Maurino-Alperovich, D Holder… - Physiological …, 2024 - iopscience.iop.org
Objective. Noisy measurements frequently cause noisy and inaccurate images in
impedance imaging. No post-processing technique exists to calculate the propagation of …

Human vagus nerve fascicular anatomy: a microCT segmentation and histological study

N Thompson, S Mastitskaya, F Iacoviello, PR Shearing… - BioRxiv, 2023 - biorxiv.org
Background: Previous research has revealed the logical mapping of fascicles in both human
somatic and pig vagus nerves, but the organization of fascicles within the human vagus …

[PDF][PDF] Spatially-selective vagus nerve stimulation and fast neural EIT of the cervical vagus nerve

N Thompson - ucl.ac.uk
Nerves contain a large number of nerve fibres, or axons, organised into bundles known as
fascicles. The new field of bioelectronics medicine, Electroceuticals, involves the electrical …

Organization of Cardiac Fibers in the Porcine Cervical Vagus Nerve Allows Spatially Selective Efferent Neuromodulation

N Thompson, E Ravagli, S Mastitskaya, R Challita… - papers.ssrn.com
Abstract Background and Objectives: Spatially-selective vagus nerve stimulation (sVNS)
offers a promising solution to mitigate the off-target effects associated with traditional VNS …