In total, twenty elements appear to be essential for the correct functioning of the human
body, half of which are metals and half are non-metals. Among those metals that are …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Copper is an important trace element that is required for essential enzymes. However, due
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …

Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …

Metal-induced toxicity and carcinogenicity, with an emphasis on the generation and role of
reactive oxygen and nitrogen species, is reviewed. Metal-mediated formation of free radicals …

Zinc is a trace element nutrient that is essential for life. This mineral serves as a cofactor for
enzymes that are involved in critical biochemical processes and it plays many structural …

Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

Research advances defining how zinc is transported into and out of cells and organelles
have increased exponentially within the past five years. Research has progressed through …

Zinc is an essential nutrient for all organisms because this metal serves as a catalytic or
structural cofactor for many different proteins. Zinc-dependent proteins are found in the …

Zinc is an essential trace element in the human body and its importance in health and
disease is appreciated. It serves as a cofactor in numerous transcription factors and enzyme …