Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy

DJ Smit, K Pantel, M Jücker - Biochemical pharmacology, 2021 - Elsevier
Circulating tumor cells (CTCs) play a crucial role in metastasis and became an emerging
topic in today's cancer research. In addition, the analysis of CTCs in liquid biopsies will be a …

[HTML][HTML] Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer

R Yang, Y Han, X Guan, Y Hong, J Meng… - Cell Communication and …, 2023 - Springer
Telomerase reverse transcriptase (TERT/hTERT) serves as the pivotal catalytic subunit of
telomerase, a crucial enzyme responsible for telomere maintenance and human genome …

Development of paper-based aptasensor for circulating tumor cells detection in the breast cancer

A Khoshroo, A Fattahi, L Hosseinzadeh - Journal of Electroanalytical …, 2022 - Elsevier
Rapid diagnosis of circulating tumor cells (CTC) is of great importance towards patients'
treatment. In this work, a simple paper-based sensing platform for label-free detection of …

[HTML][HTML] Unlocking Translational Potential: Conditionally Reprogrammed Cells in Advancing Breast Cancer Research

D Daneshdoust, M Luo, Z Li, X Mo, S Alothman… - Cells, 2023 - mdpi.com
Preclinical in vitro models play an important role in studying cancer cell biology and
facilitating translational research, especially in the identification of drug targets and drug …

Biofabricated functionalized graphene quantum dots (fGQDs): unraveling its fluorescence sensing mechanism of human telomerase reverse transcriptase (hTERT) …

RS Tade, PO Patil - Biomedical Materials, 2022 - iopscience.iop.org
Lung cancer (LC) is a deadly malignancy that is posing a serious threat to human health.
Therefore, early detection of LC biomarkers is the key to reducing LC-related fatalities …

[HTML][HTML] Conditionally reprogrammed cells and robotic high-throughput screening for precision cancer therapy

F Alkhilaiwi - Frontiers in Oncology, 2021 - frontiersin.org
Cancer is a devastating disease that takes the lives of millions of people globally every year.
Precision cancer therapy is based on a patient's tumor histopathology, expression analyses …

[HTML][HTML] Detection of Circulating Tumor Cells Using Three-dimensional and Conditionally Reprogrammed Culture Methods

C Park, YJ Jeong, SH Park, DD Kim… - Laboratory Medicine …, 2021 - synapse.koreamed.org
Background Circulating tumor cells (CTCs) are rare in the circulation of patients with tumors
and are very difficult to detect. In this study, we cultured CTCs in a three-dimensionally …

[PDF][PDF] Assessing the Feasibility and Clinical Implications of multimarker RT-qPCR Profiling for Circulating Tumor Cell Detection in Breast Cancer Patients: A Pilot …

M Ali, HMH Khaliq, A Batool, K Bano, A Arshad - researchgate.net
Objective: We primarily aimed to detect, isolate and enumerate circulating tumor cells with
the help of a panel of markers in a cohort of breast cancer patients in Pakistani Population …