Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Ferroptosis is a unique type of non-apoptotic cell death resulting from the unrestrained
occurrence of peroxidized phospholipids, which are subject to iron-mediated production of …

Rationale: Maintaining iron homeostasis is essential for proper cardiac function. Both iron
deficiency and iron overload are associated with cardiomyopathy and heart failure via …

Iron is biologically essential, but also potentially toxic; as such it is tightly controlled at cell
and systemic levels to prevent both deficiency and overload. Iron regulatory proteins post …

Ferroptosis, a type of regulated cell death driven by iron-dependent phospholipid
peroxidation, has captured much attention in the field of nanomedicine since it was coined in …

Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and …

Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …

Hemochromatosis (HC) is a genetically heterogeneous disorder in which uncontrolled
intestinal iron absorption may lead to progressive iron overload (IO) responsible for …

The maintenance of iron homeostasis is essential for proper endocrine function. A growing
body of evidence suggests that iron imbalance is a key factor in the development of several …