Therapeutic potential of ectopic olfactory and taste receptors
SJ Lee, I Depoortere, H Hatt - Nature Reviews Drug Discovery, 2019 - nature.com
Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …
[HTML][HTML] An evolutionary perspective on food and human taste
PAS Breslin - Current Biology, 2013 - cell.com
The sense of taste is stimulated when nutrients or other chemical compounds activate
specialized receptor cells within the oral cavity. Taste helps us decide what to eat and …
specialized receptor cells within the oral cavity. Taste helps us decide what to eat and …
Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …
Oleogustus: the unique taste of fat
Considerable mechanistic data indicate there may be a sixth basic taste: fat. However,
evidence demonstrating that the sensation of nonesterified fatty acids (NEFA, the proposed …
evidence demonstrating that the sensation of nonesterified fatty acids (NEFA, the proposed …
Taste of fat: a sixth taste modality?
P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …
decade, the mechanisms responsible for this specific eating behavior have been actively …
[HTML][HTML] The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects
The precise orosensory inputs engaged for dietary lipids detection in humans are unknown.
We evaluated whether a common single nucleotide polymorphism (rs1761667) in the CD36 …
We evaluated whether a common single nucleotide polymorphism (rs1761667) in the CD36 …
Sugar reduction without compromising sensory perception. An impossible dream?
Sugar reduction is a major technical challenge for the food industry to address in response
to public health concerns regarding the amount of added sugars in foods. This paper …
to public health concerns regarding the amount of added sugars in foods. This paper …
[HTML][HTML] Reduced dietary intake of simple sugars alters perceived sweet taste intensity but not perceived pleasantness
PM Wise, L Nattress, LJ Flammer… - The American journal of …, 2016 - Elsevier
Background: Individuals who adhere to reduced-sodium diets come to prefer less salt over
time, but it is unclear whether sweet taste perception is modulated by reduced sugar intake …
time, but it is unclear whether sweet taste perception is modulated by reduced sugar intake …
Endocannabinoids in the Gut
NV DiPatrizio - Cannabis and cannabinoid research, 2016 - liebertpub.com
Cannabis has been used medicinally for centuries to treat a variety of disorders, including
those associated with the gastrointestinal tract. The discovery of our bodies' own “cannabis …
those associated with the gastrointestinal tract. The discovery of our bodies' own “cannabis …
Role of gut nutrient sensing in stimulating appetite and conditioning food preferences
A Sclafani, K Ackroff - American Journal of Physiology …, 2012 - journals.physiology.org
The discovery of taste and nutrient receptors (chemosensors) in the gut has led to intensive
research on their functions. Whereas oral sugar, fat, and umami taste receptors stimulate …
research on their functions. Whereas oral sugar, fat, and umami taste receptors stimulate …