Paeonol: pharmacological effects and mechanisms of action

L Zhang, D Li, L Liu - International Immunopharmacology, 2019 - Elsevier
Paeonia suffruticosa possesses various medicinal benefits and has been used extensively
in traditional oriental medicine for thousands of years. Paeonol is the main component …

A Pharmacological Review of Bioactive Constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch

S Parker, B May, C Zhang, AL Zhang… - Phytotherapy …, 2016 - Wiley Online Library
The roots of two peony species, Paeonia lactiflora Pallas and Paeonia veitchii Lynch are
routinely referred to as either chishao (赤芍) or baishao (白芍). This paper reviews the …

Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells

L Gao, Z Wang, D Lu, J Huang, J Liu, L Hong - Cell Death & Disease, 2019 - nature.com
Paeonol (Pae), a phenolic acid compound isolated from the Moutan Cortex, was previously
demonstrated to exert multiple anticancer effects. The rational control of autophagy has …

Potential therapeutic compounds from traditional Chinese medicine targeting endoplasmic reticulum stress to alleviate rheumatoid arthritis

IRSR Dias, HH Lo, K Zhang, BYK Law, AA Nasim… - Pharmacological …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease which affects about
0.5–1% of people with symptoms that significantly impact a sufferer's lifestyle. The cells …

Paeonol inhibits the malignancy of Apatinib-resistant gastric cancer cells via LINC00665/miR-665/MAPK1 axis

M Li, O Cai, Y Yu, S Tan - Phytomedicine, 2022 - Elsevier
Background Paeonol is the extractive of Paeonia suffruticosa Andr and is reported to reverse
the chemotherapy resistance of cancer cells. The present study explores the role of paeonol …

Origins, Phytochemistry, Pharmacology, Analytical Methods and Safety of Cortex Moutan (Paeonia suffruticosa Andrew): A Systematic Review

Z Wang, C He, Y Peng, F Chen, P Xiao - Molecules, 2017 - mdpi.com
Cortex Moutan (CM), a well-known traditional Chinese medicine, is commonly used for
treating various diseases in China and other eastern Asian countries. Recorded in …

Progress in active compounds effective on ulcerative colitis from Chinese medicines

CAO Si-Yu, YE Sheng-Jie, W Wei-Wei, W Bing… - Chinese journal of …, 2019 - Elsevier
Ulcerative colitis (UC), a chronic inflammatory disease affecting the colon, has a rising
incidence worldwide. The known pathogenesis is multifactorial and involves genetic …

Traditional uses, phytochemistry, pharmacology, and pharmacokinetics of the root bark of Paeonia x suffruticosa andrews: A comprehensive review

J Liu, X Li, H Bai, X Yang, J Mu, R Yan… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Moutan Cortex (MC), commonly known as “Mu
dan pi”, refers to the dried root bark of Paeonia x suffruticosa Andrews and is broadly used …

Surgical stress response and promotion of metastasis in colorectal cancer: a complex and heterogeneous process

C Behrenbruch, C Shembrey, S Paquet-Fifield… - Clinical & experimental …, 2018 - Springer
Surgery remains the curative treatment modality for colorectal cancer in all stages, including
stage IV with resectable liver metastasis. There is emerging evidence that the stress …

Pharmacological effects and mechanisms of paeonol on antitumor and prevention of side effects of cancer therapy

X Chang, X Feng, M Du, S Li, J Wang… - Frontiers in …, 2023 - frontiersin.org
Cancer represents one of the leading causes of mortality worldwide. Conventional clinical
treatments include radiation therapy, chemotherapy, immunotherapy, and targeted therapy …