Objective: Therapeutic approaches with bronchioalveolar lavage are currently used in
infants with severe alveolar space-occupying material. In many circumstances …

Respiratory distress syndrome (RDS) is a disease characterized by neonatal respiratory
failure. It is principally caused by a deficiency of pulmonary surfactant, which is a lipoprotein …

Douglas F. Willson, Patricia R. Chess, Zhengdong Wang, and Robert H. Notter dampened
by initial unsuccessful attempts by Robillard et al.[9] and Chu et al.[10, 11] in the 1960s to …

Two infants presenting with respiratory distress in the first 24 h of life are described. Both
patients underwent extensive investigation before the diagnosis of surfactant protein B …

A considerable number of biophysical and biochemical studies has increased our
understanding of the surface activity of surfactant proteins B and C (SP-B, SP-C) in the …

Mature lung surfactant protein C (SP‐C) corresponds to residues 24–58 of the 21 kDa proSP‐
C. A late processing intermediate, SP‐Ci, corresponding to residues 12–58 of proSP‐C …

Abstract Surfactant protein C (SP-C) is a hydrophobic lipoprotein necessary for lowering
alveolar surface tension and lung defense mechanisms. Defects in its function due to …

FVIIa to the site of endothelial injury (3). TF pathway inhibitor (TFPI) is a potent inhibitor of
the FVIIa/TF catalytic complex. Plasma levels of TFPI To the Editor: are increased in systemic …

OBJECTIVE: To determine if high-frequency oscillatory ventilation and neuromuscular
blockade improve oxygenation and chest radiographic appearance more effectively than …

Pulmonary alveolar proteinosis is a rare lung disease characterized by the accumulation of
lipoproteinaceous material within the alveoli. Analysis of the lipoproteinaceous materials …