We investigated the histological and molecular characteristics of pulmonary alveolar
proteinosis (PAP) in two siblings (a brother and sister) who did not exhibit respiratory …

Mature SP-C is a 4.2 kDa transmembrane protein which is uniquely expressed in the
alveolar type II cell. Human SP-C is generated via multistep proteolytic cleavage of both the …

Background: Among respiratory support techniques, nasal continuous positive airway
pressure (NCPAP) and mechanical ventilation (MV) are more known for their effectivity in …

Publisher Summary This chapter outlines current knowledge on pulmonary surface and
surfactant investigations and targets at modelling of the surface-related interactions between …

Interstitial lung disease in children is uncommon. It usually presents with the gradual onset
of increasing respiratory symptoms including tachypnoea, effort dyspnoea and cyanosis. In …

Major scientific advances in prenatal and neonatal physiology have provided the basis for
improved outcomes for preterm and other infants with disorders causing respiratory failure …

Para valorar la incidencia de la enfermedad de membrana hialina (EMH), caracterizar la
población de riesgo, evaluar el tratamiento instaurado y las complicaciones más frecuentes …

Gene therapy has been considered as a viable therapeutic option for life limiting genetic
diseases (eg Cystic Fibrosis (CF) and ß-Thalassemia) lacking conventional therapy. Over …

Wir berichten über ein reifes weibliches Neugeborenes mit unauffälliger Familienanamnese,
das wenige Stunden postpartal mit einer Tachydyspnoe und zunehmender Zyanose …

In this issue of The Journal, Soto-Cárdenas, et al examine the frequency of a genetic
polymorphism that is associated with elevated surfactant protein D (SP-D) levels and assess …