This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics
and underlying mechanisms, including status epilepticus, drug and surgical treatments …

Understanding the aetiology of epilepsy is essential both for clinical management of patients
and for conducting neurobiological research that will direct future therapies. The aetiology of …

This review reports the available evidence on the activation of the innate and adaptive
branches of the immune system and the related inflammatory processes in epileptic …

Importance Autoimmune epilepsy is an underrecognized condition, and its true incidence is
unknown. Identifying patients with an underlying autoimmune origin is critical because these …

We have reviewed the literature of immune therapy in autoimmune encephalitis associated
with antibodies to cell surface antigens including N-methyl-D-aspartate receptor (NMDAR) …

The identification of the aetiology of a patient's epilepsy is instrumental in the diagnosis,
prognostic counselling and management of the epilepsies. Indeed, the aetiology can be …

The field of autoimmune epilepsy has evolved substantially in the last few decades with
discovery of several neural autoantibodies and improved mechanistic understanding of …

Glutamic acid decarboxylase (GAD) is an intracellular enzyme whose physiologic function is
the decarboxylation of glutamate to gamma-aminobutyric acid (GABA), the main inhibitory …

Although seizures are frequent in all types of autoimmune encephalitis, the risk for chronic
epilepsy is dependent on the antigen: lower if located on the cell-surface, and higher if …

Objective To validate predictive models for neural antibody positivity and immunotherapy
response in epilepsy. Methods We conducted a retrospective study of epilepsy cases at …