The COVID-19 pandemic has exacerbated mortality rates among immunocompromised
patients, accentuating the need for novel, targeted therapies. Transplant recipients, with their …

Evidence shows that there is a synergistic, bidirectional association between cancer and
aging with many shared traits. Age itself is a risk factor for the onset of most cancers, while …

Introduction Development and worsening of most common neurodegenerative diseases,
such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis, have been …

Abstract Calcium (Ca 2+) homeostasis is crucial for maintaining physiological processes in
the body, and disruptions in Ca 2+ signaling can lead to various pathological conditions …

The post-acute COVID-19 syndrome (PACS) is characterized by the persistence of
fluctuating symptoms over three months from the onset of the possible or confirmed COVID …

The development of age-related cardiovascular (CV) dysfunction increases the risk of CV
disease as well as other chronic age-associated disorders, including chronic kidney …

Immunosenescence is a therapeutic target for frailty in older adults: a narrative review - PMC
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The objective of this study was to characterize frailty and resilience in people evaluated for
Post-Acute COVID-19 Syndrome (PACS), in relation to quality of life (QoL) and Intrinsic …

Older age is one of the strongest risk factors for severe COVID-19. In this study, we
determined whether age-associated cellular senescence contributes to the severity of …

The most severe alterations in Coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) infection are seen in the lung …