Background Tuberculosis is a bacterial infectious disease, which affects different parts of a
human body, mainly lungs and can lead to the patient's death. The aim of this study is to …

Objective To investigate the mutations within the whole rpoB gene of Mycobacterium
tuberculosis and analyze their effects on rifampin (RIF) resistance based on crystal structure …

Background: Despite the implementation of the national control program, tuberculosis is one
of the greatest health problems in Iran. The prevalence of different strains in specific ethnic …

Abstract Background & objective Mycobacterium Tuberculosis (Mtb) is one of the most gram
positive dangerous pathogenic bacteria cause tuberculosis (TB) and cause hundreds …

Despite a Mycobacterium tuberculosis control programme and anti-tuberculosis drugs, drug-
resistant tuberculosis (DR-TB) is one of the most serious public health issues worldwide …

Objectives: Molecular approaches to identifying resistance-conferring mutations suggest a
revolution in the field of tuberculosis. The aim of the study was to determine the association …

Introduction: Tuberculosis remains the leading causes of death worldwide with frequencies
of mutations in rifampicin and isoniazid resistant Mycobacterium tuberculosis isolates …

Accurate and timely detection of drug resistance can minimize the risk of further resistance
development and lead to effective treatment. The aim of this study was to determine the …

Tuberculosis (TB), caused by the Mycobacterium tuberculosis infection, continues to be a
leading cause of morbidity and mortality in developing countries. Resistance to the first-line …

Background: The spread of drug-resistant tuberculosis (TB) is one of the major public health
problems through the world. Surveillance of anti-TB drug resistance is essential for …