Genetics of obsessive-compulsive disorder

B Mahjani, K Bey, J Boberg, C Burton - Psychological medicine, 2021 - cambridge.org
BackgroundObsessive-compulsive disorder (OCD) is a psychiatric disorder with multiple
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades …

[HTML][HTML] Effects of exercise on cognitive performance in children and adolescents with ADHD: potential mechanisms and evidence-based recommendations

L Christiansen, MM Beck, N Bilenberg… - Journal of clinical …, 2019 - mdpi.com
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with a
complex symptomatology, and core symptoms as well as functional impairment often persist …

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

R Karlsson Linnér, TT Mallard, PB Barr… - Nature …, 2021 - nature.com
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …

Identification of common genetic risk variants for autism spectrum disorder

J Grove, S Ripke, TD Als, M Mattheisen, RK Walters… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

Updated European Consensus Statement on diagnosis and treatment of adult ADHD

JJS Kooij, D Bijlenga, L Salerno, R Jaeschke… - European …, 2019 - cambridge.org
Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common
psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

D Demontis, RK Walters, J Martin, M Mattheisen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

[HTML][HTML] Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

DM Howard, MJ Adams, M Shirali, TK Clarke… - Nature …, 2018 - nature.com
Depression is a polygenic trait that causes extensive periods of disability. Previous genetic
studies have identified common risk variants which have progressively increased in number …

[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia

C Doust, P Fontanillas, E Eising, SD Gordon, Z Wang… - Nature …, 2022 - nature.com
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …

[HTML][HTML] Reduced microbiome alpha diversity in young patients with ADHD

A Prehn-Kristensen, A Zimmermann, L Tittmann… - PloS one, 2018 - journals.plos.org
ADHD is a psychiatric disorder which is characterized by hyperactivity, impulsivity and
attention problems. Due to recent findings of microbial involvement in other psychiatric …

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

NR Wray, S Ripke, M Mattheisen, M Trzaskowski… - Nature …, 2018 - nature.com
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …