Meningioma: not always a benign tumor. A review of advances in the treatment of meningiomas

I Maggio, E Franceschi, A Tosoni, VD Nunno… - CNS …, 2021 - Taylor & Francis
Meningiomas are the most common primary intracranial tumors. The majority of
meningiomas are benign, but they can present different grades of dedifferentiation from …

Epidemiology and etiology of meningioma

J Wiemels, M Wrensch, EB Claus - Journal of neuro-oncology, 2010 - Springer
Although most meningiomas are encapsulated and benign tumors with limited numbers of
genetic aberrations, their intracranial location often leads to serious and potentially lethal …

DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management

F Nassiri, Y Mamatjan, S Suppiah… - Neuro …, 2019 - academic.oup.com
Background Variability in standard-of-care classifications precludes accurate predictions of
early tumor recurrence for individual patients with meningioma, limiting the appropriate …

Pathological classification and molecular genetics of meningiomas

C Mawrin, A Perry - Journal of neuro-oncology, 2010 - Springer
Meningiomas are extremely common adult brain tumors originating from meningeal
coverings of the brain and spinal cord. While most are slowly growing Word Health …

Integrated genomic analyses of de novo pathways underlying atypical meningiomas

AS Harmancı, MW Youngblood, VE Clark… - Nature …, 2017 - nature.com
Meningiomas are mostly benign brain tumours, with a potential for becoming atypical or
malignant. On the basis of comprehensive genomic, transcriptomic and epigenomic …

Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia …

Z Li, J Zhang, H Zheng, C Li, J Xiong, W Wang… - Journal of Experimental …, 2019 - Springer
Background Accumulating evidence demonstrates the oncogenic roles of lncRNA (long non-
coding RNA) molecules in a wide variety of cancer types including glioma. Equally …

Molecular and translational advances in meningiomas

S Suppiah, F Nassiri, WL Bi, IF Dunn… - Neuro …, 2019 - academic.oup.com
Meningiomas are the most common primary intracranial neoplasm. The current World
Health Organization (WHO) classification categorizes meningiomas based on …

[HTML][HTML] Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma

Z Du, M Abedalthagafi, AA Aizer, AR McHenry… - Oncotarget, 2015 - ncbi.nlm.nih.gov
There are no effective medical treatments for WHO grade III (anaplastic) meningioma.
Patients with this high-grade malignancy have a median survival of less than two years …

Pathology concordance levels for meningioma classification and grading in NRG Oncology RTOG Trial 0539

CL Rogers, A Perry, S Pugh, MA Vogelbaum… - Neuro …, 2015 - academic.oup.com
Background With advances in the understanding of histopathology on outcome, accurate
meningioma grading becomes critical and drives treatment selection. The 2000 and 2007 …

Proposal for a new risk stratification classification for meningioma based on patient age, WHO tumor grade, size, localization, and karyotype

PH Domingues, P Sousa, A Otero… - Neuro …, 2014 - academic.oup.com
Background Tumor recurrence remains the major clinical complication of meningiomas, the
majority of recurrences occurring among WHO grade I/benign tumors. In the present study …