Crop improvement by genome editing involves the targeted alteration of genes to improve
plant traits, such as stress tolerance, disease resistance or nutritional content. Techniques …

Common wheat (Triticum aestivum) is one of the most widely cultivated and consumed crops
globally. In the face of limited arable land and climate changes, it is a great challenge to …

Background Base editing is a powerful tool for artificial evolution to create allelic diversity
and improve agronomic traits. However, the great evolutionary potential for every sgRNA …

Cytosine base editors (CBEs) and adenine base editors (ABEs) enable precise C-to-T and A-
to-G edits. Recently, ABE8e, derived from TadA-8e, enhances A-to-G edits in mammalian …

CRISPR-mediated base editors have been widely used to correct defective alleles and
create novel alleles by artificial evolution for the rapid genetic improvement of crops. The …

The programmable CRISPR-Cas genome editing technology, adopted from prokaryotic
adaptive immune systems, has revolutionized genome engineering in plants (Liu et al …

Dual base editors (DBEs) enable simultaneous A‐to‐G and C‐to‐T conversions, expanding
mutation types. However, low editing efficiency and narrow targeting range limit the …

Together with rice, weeds strive for nutrients and space in farmland, resulting in reduced rice
yield and quality. Planting herbicide‐resistant rice varieties is one of the effective ways to …

We have developed a dual base editor, rA&GBE, by fusing adenine and glycosylase base
editors. It can induce up to eight types of mutations in T 0-generation rice, including single …