The role of miRNAs in liver diseases: Potential therapeutic and clinical applications
MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …
transcriptionally to regulate gene expression by binding to particular mRNA targets and …
[HTML][HTML] Alcohol-associated liver disease
B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …
and comprises a spectrum of several different disorders, including simple steatosis …
Flexible photoelectrochemical biosensor for ultrasensitive microRNA detection based on concatenated multiplex signal amplification
Y Zhao, J Xiang, H Cheng, X Liu, F Li - Biosensors and Bioelectronics, 2021 - Elsevier
Precise microRNA (miRNA) analysis is significant importance for early disease diagnosis.
Herein, a novel flexible photoelectrochemical (PEC) biosensor for miRNA determination was …
Herein, a novel flexible photoelectrochemical (PEC) biosensor for miRNA determination was …
[HTML][HTML] Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
[HTML][HTML] MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
miRNAs inspirations in hepatocellular carcinoma: detrimental and favorable aspects of key performers
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths
worldwide. HCC initiation, progression, and therapy failure are all influenced by various …
worldwide. HCC initiation, progression, and therapy failure are all influenced by various …
[HTML][HTML] Functional roles of chemokine receptor CCR2 and its ligands in liver disease
S She, L Ren, P Chen, M Wang, D Chen… - Frontiers in …, 2022 - frontiersin.org
Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …
immune cells within tissues and are critical for the function of the immune system. CCR2 …
[HTML][HTML] Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH)
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
[HTML][HTML] Role of neutrophils in the pathogenesis of nonalcoholic steatohepatitis
Nonalcoholic fatty liver disease (NAFLD) includes a spectrum of liver disorders, from fatty
liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma …
liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma …
[HTML][HTML] Circular RNA circBCBM1 promotes breast cancer brain metastasis by modulating miR-125a/BRD4 axis
B Fu, W Liu, C Zhu, P Li, L Wang, L Pan… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) play critical roles in tumorigenesis and the progression of various
cancers. We previously identified a novel upregulated circRNA, circBCBM1 …
cancers. We previously identified a novel upregulated circRNA, circBCBM1 …