Understanding regeneration through proteomics
Regeneration is a complex cellular process that, rather than simply forming a scar following
injury, the animal forms a new functional tissue. Regeneration is a widespread process …
injury, the animal forms a new functional tissue. Regeneration is a widespread process …
RNA-Seq transcriptome profiling in three liver regeneration models in rats: comparative analysis of partial hepatectomy, ALLPS, and PVL
D Colak, O Al-Harazi, OM Mustafa, F Meng… - Scientific Reports, 2020 - nature.com
The liver is a unique organ that has a phenomenal capacity to regenerate after injury.
Different surgical procedures, including partial hepatectomy (PH), intraoperative portal vein …
Different surgical procedures, including partial hepatectomy (PH), intraoperative portal vein …
Changes in the mitochondrial proteome in human hepatocytes in response to alpha-amanitin hepatotoxicity
M Wang, Y Chen, Z Guo, C Yang, J Qi, Y Fu, Z Chen… - Toxicon, 2018 - Elsevier
Amanitin-induced apoptosis is proposed to have a significant effect on the pathogenesis of
liver damage. However, few reports have focused on proteome changes induced by α …
liver damage. However, few reports have focused on proteome changes induced by α …
Does mechanocrine signaling by liver sinusoidal endothelial cells offer new opportunities for the development of anti-fibrotics?
S Soydemir, O Comella, D Abdelmottaleb… - Frontiers in …, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSECs) are specialized endothelial cells that have
essential roles in normal liver homeostasis, and are also involved in disease processes. The …
essential roles in normal liver homeostasis, and are also involved in disease processes. The …
Serum proteomic signature of human chagasic patients for the identification of novel potential protein biomarkers of disease
JJ Wen, MP Zago, S Nunez, S Gupta, FN Burgos… - Molecular & Cellular …, 2012 - ASBMB
Chagas disease is initiated upon infection by Trypanosoma cruzi. Among the health
consequences is a decline in heart function, and the pathophysiological mechanisms …
consequences is a decline in heart function, and the pathophysiological mechanisms …
Proteomic analysis of the regenerating liver following 2/3 partial hepatectomy in rats
XG Chen, CS Xu - Biological research, 2014 - Springer
Background Liver regeneration (LR) after 2/3 partial hepatectomy (PH) is one of the most
studied models of cell, organ, and tissue regeneration. Although the transcriptional profile …
studied models of cell, organ, and tissue regeneration. Although the transcriptional profile …
Myofibroblasts are important contributors to human hepatocellular carcinoma: evidence for tumor promotion by proteome profiling
A Slany, V Haudek‐Prinz, H Zwickl, S Stättner… - …, 2013 - Wiley Online Library
Liver cancer typically occurs with a background of chronic fibrosis, characterized by the
accumulation of myofibroblast‐like cells. We performed 2 D‐PAGE‐based comparative …
accumulation of myofibroblast‐like cells. We performed 2 D‐PAGE‐based comparative …
[PDF][PDF] 质谱MRM 技术结合稳定同位素标记法的应用进展
齐林玉, 姜淼, 郭艳, 王迎, 陈平 - 生命科学研究, 2015 - smkx.hunnu.edu.cn
定量检测是生物化学研究中最常见的一种分析方法, 可以显示蛋白质的差异表达及翻译后修饰
情况, 有助于了解酶的活性状态尧信号通路及活性分子间相互作用网络遥生物质谱以其高通量尧 …
情况, 有助于了解酶的活性状态尧信号通路及活性分子间相互作用网络遥生物质谱以其高通量尧 …
Proteomic analysis of immediate‐early response plasma proteins after 70% and 90% partial hepatectomy
Aim Partial hepatectomy (PH) induces robust hepatic regenerative and metabolic responses
that are considered to be triggered by humoral factors. The aim of the study was to identify …
that are considered to be triggered by humoral factors. The aim of the study was to identify …
Con A 型差异糖蛋白在大鼠肝再生中的作用研究
杨彦杰, 杨军英, 张亚磊, 耿小芳, 徐存拴 - 西北师范大学学报: 自然科学版, 2013 - cqvip.com
为研究差异糖蛋白在肝再生中的作用, 运用ConA 凝集素固相亲和层析, 双向电泳和质谱等技术
对大鼠再生肝的糖蛋白质组学进行研究, 共鉴定出123 种蛋白. 有117 种蛋白具有潜在的N-或0 …
对大鼠再生肝的糖蛋白质组学进行研究, 共鉴定出123 种蛋白. 有117 种蛋白具有潜在的N-或0 …