Diffusion imaging of brain tumors

SE Maier, Y Sun, RV Mulkern - NMR in biomedicine, 2010 - Wiley Online Library
MRI offers a tremendous armamentarium of different methods that can be employed in brain
tumor characterization. MR diffusion imaging has become a widely accepted method to …

[图书][B] The handbook of biomarkers

KK Jain, KK Jain - 2010 - Springer
There are several definitions of biomarkers. A biomarker is a characteristic that can be
objectively measured and evaluated as an indicator of a physiological as well as a …

Noninvasive mapping of water diffusional exchange in the human brain using filter‐exchange imaging

M Nilsson, J Lätt, D van Westen… - Magnetic resonance …, 2013 - Wiley Online Library
We present the first in vivo application of the filter‐exchange imaging protocol for diffusion
MRI. The protocol allows noninvasive mapping of the rate of water exchange between …

Diffusion-weighted MR imaging derived apparent diffusion coefficient is predictive of clinical outcome in primary central nervous system lymphoma

RF Barajas, JL Rubenstein, JS Chang… - American Journal …, 2010 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: There is evidence that increased tumor cellular density
within diagnostic specimens of primary central nervous system lymphoma (PCNSL) may …

Functional diffusion map as an early imaging biomarker for high-grade glioma: correlation with conventional radiologic response and overall survival

DA Hamstra, CJ Galbán, CR Meyer… - Journal of clinical …, 2008 - ascopubs.org
Purpose Assessment of radiologic response (RR) for brain tumors utilizes the Macdonald
criteria 8 to 10 weeks from the start of treatment. Diffusion magnetic resonance imaging …

The role of imaging in radiation therapy planning: past, present, and future

GC Pereira, M Traughber… - BioMed research …, 2014 - Wiley Online Library
The use of ionizing radiation for cancer treatment has undergone extraordinary development
during the past hundred years. The advancement of medical imaging has been critical in …

Value of diffusion-weighted magnetic resonance imaging for prediction and early assessment of response to neoadjuvant radiochemotherapy in rectal cancer …

M Lambrecht, V Vandecaveye, F De Keyzer… - International Journal of …, 2012 - Elsevier
PURPOSE: To evaluate diffusion-weighted magnetic resonance imaging (DWI) for response
prediction before and response assessment during and early after preoperative …

Deep learning approaches using 2D and 3D convolutional neural networks for generating male pelvic synthetic computed tomography from magnetic resonance …

J Fu, Y Yang, K Singhrao, D Ruan, FI Chu… - Medical …, 2019 - Wiley Online Library
Purpose The improved soft tissue contrast of magnetic resonance imaging (MRI) compared
to computed tomography (CT) makes it a useful imaging modality for radiotherapy treatment …

Lessons from anti–vascular endothelial growth factor and anti–vascular endothelial growth factor receptor trials in patients with glioblastoma

C Lu-Emerson, DG Duda, KE Emblem… - Journal of Clinical …, 2015 - ascopubs.org
Treatment of glioblastoma (GBM), the most common primary malignant brain tumor in adults,
remains a significant unmet need in oncology. Historically, cytotoxic treatments provided …

Evaluation of the functional diffusion map as an early biomarker of time-to-progression and overall survival in high-grade glioma

DA Hamstra, TL Chenevert, BA Moffat… - Proceedings of the …, 2005 - National Acad Sciences
Diffuse malignant gliomas, the most common type of brain tumor, carry a dire prognosis and
are poorly responsive to initial treatment. The response to treatment is typically evaluated by …