SIRT1 and aging related signaling pathways

C Chen, M Zhou, Y Ge, X Wang - Mechanisms of ageing and development, 2020 - Elsevier
Aging is a biological phenomenon in which the structure and function of organisms declining
with the increasing of age. It has become a major risk factor of human diseases, including …

[HTML][HTML] As a modulator, multitasking roles of SIRT1 in respiratory diseases

Y Zhou, F Zhang, J Ding - Immune Network, 2022 - ncbi.nlm.nih.gov
As far the current severe coronavirus disease 2019 (COVID-19), respiratory disease is still
the biggest threat to human health. In addition, infectious respiratory diseases are …

Construction of potential miRNA–mRNA regulatory network in COPD plasma by bioinformatics analysis

M Zhu, M Ye, J Wang, L Ye, M Jin - International journal of chronic …, 2020 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) has become a major cause of
morbidity and mortality worldwide. Increasing evidence indicates that aberrantly expressed …

Associations of the NRF2/KEAP1 pathway and antioxidant defense gene polymorphisms with chronic obstructive pulmonary disease

GF Korytina, LZ Akhmadishina, YG Aznabaeva… - Gene, 2019 - Elsevier
Background and objective Chronic obstructive pulmonary disease (COPD) is a complex
chronic inflammatory disease of the respiratory system affecting primarily distal respiratory …

Identification of genetic biomarkers, drug targets and agents for respiratory diseases utilising integrated bioinformatics approaches

FF Ahmed, AD Das, MJ Sumi, MZ Islam, MS Rahman… - Scientific Reports, 2023 - nature.com
Respiratory diseases (RD) are significant public health burdens and malignant diseases
worldwide. However, the RD-related biological information and interconnection still need to …

Identification and validation of autophagy-related genes in chronic obstructive pulmonary disease

S Sun, Y Shen, J Wang, J Li, J Cao… - International journal of …, 2021 - Taylor & Francis
Purpose Autophagy plays essential roles in the development of COPD. We aim to identify
and validate the potential autophagy-related genes of COPD through bioinformatics analysis …

Comparative transcriptome analysis of unfractionated peripheral blood leukocytes after exercise in human

M Nie, Q Liu, R Jia, Z Li, X Li, X Meng - Scientific Reports, 2023 - nature.com
Exercise has profound but variable effects on the immune system. However, only limited
information exists about the changes of exercise-induced gene expression in whole immune …

Accelerated lung aging and chronic obstructive pulmonary disease

YS Yoon, M Jin, DD Sin - Expert review of respiratory medicine, 2019 - Taylor & Francis
Introduction: The prevalence of chronic obstructive pulmonary disease (COPD) increases
exponentially with aging. Its pathogenesis, however, is not well known and aside from …

[HTML][HTML] Quantitative assessment of erector spinae muscles in patients with Mycobacterium avium complex lung disease

T Asakura, Y Yamada, S Suzuki, H Namkoong… - Respiratory …, 2018 - Elsevier
Background and objective No reports exist regarding skeletal muscle involvement in
patients with Mycobacterium avium complex lung disease (MAC-LD). The cross-sectional …

Computed tomography-based body composition measures in COPD and their association with clinical outcomes: A systematic review

JM Nicholson, CE Orsso… - Chronic Respiratory …, 2022 - journals.sagepub.com
Background Computed tomography (CT) is commonly utilized in chronic obstructive
pulmonary disease (COPD) for lung cancer screening and emphysema characterization …