Immune response in COVID-19: what is next?
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …
SARS-CoV-2 and the host cell: a tale of interactions
M Pizzato, C Baraldi, G Boscato Sopetto… - Frontiers in …, 2022 - frontiersin.org
The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular …
course of the infection are macroscopic consequences of a multifaceted molecular …
The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …
Immunosenescence and COVID-19
JM Witkowski, T Fulop, E Bryl - Mechanisms of ageing and development, 2022 - Elsevier
Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …
believed that changes occurring in ageing immune system are responsible for increased …
COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy
As the COVID-19 pandemic continues into its third year, emerging data indicates increased
risks associated with SARS-CoV-2 infection during pregnancy, including pre-eclampsia …
risks associated with SARS-CoV-2 infection during pregnancy, including pre-eclampsia …
Phase separation by the SARS-CoV-2 nucleocapsid protein: Consensus and open questions
SM Cascarina, ED Ross - Journal of Biological Chemistry, 2022 - ASBMB
In response to the recent SARS-CoV-2 pandemic, a number of labs across the world have
reallocated their time and resources to better our understanding of the virus. For some …
reallocated their time and resources to better our understanding of the virus. For some …
Protein post-translational modification in SARS-CoV-2 and host interaction
N Cheng, M Liu, W Li, BY Sun, D Liu, G Wang… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 can cause lung diseases, such as pneumonia and acute respiratory distress
syndrome, and multi-system dysfunction. Post-translational modifications (PTMs) related to …
syndrome, and multi-system dysfunction. Post-translational modifications (PTMs) related to …
[HTML][HTML] NLRP3 inflammasome activation and SARS-CoV-2-mediated hyperinflammation, cytokine storm and neurological syndromes
Despite the introduction of vaccines and drugs for SARS-CoV-2, the COVID-19 pandemic
continues to spread throughout the world. In severe COVID-19 patients, elevated levels of …
continues to spread throughout the world. In severe COVID-19 patients, elevated levels of …
Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection
H Ren, C Ma, H Peng, B Zhang, L Zhou, Y Su, X Gao… - Biology Direct, 2021 - Springer
SARS-CoV-2 infection could cause severe acute respiratory syndrome, largely attributed to
dysregulated immune activation and extensive lung tissue damage. However, the …
dysregulated immune activation and extensive lung tissue damage. However, the …
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity
Summary G3BP1/2 are paralogous proteins that promote stress granule formation in
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …