Periodontal disease (PD) is one of the most common inflammatory oral diseases, affecting
approximately 47% of adults aged 30 years or older in the United States. If not treated …

Statins, inhibitors of the hydroxymethylglutaryl-CoA (HMG-CoA) reductase enzyme, are
molecules of fungal origin. By inhibiting a key step in the sterol biosynthetic pathway statins …

Background Considering the role of the inflammatory host response in the pathogenesis of
periodontitis, different host modulators have been proposed to enhance the outcomes of non …

Thorat MK, Pradeep AR, Pallavi B. Clinical effect of autologous platelet‐rich fibrin in the
treatment of intra‐bony defects: a controlled clinical trial. J Clin Periodontol 2011; 38: 925 …

Background: Platelet‐rich fibrin (PRF), an intimate assembly of cytokines, glycan chains, and
structural glycoproteins enmeshed within a slowly polymerized fibrin network, has the …

Periodontitis is a biofilm‐induced, host‐mediated inflammatory disease that results in
periodontal tissue destruction. The design of functional biomaterials based on disease …

The pleiotropic effects of statins have been evaluated to assess their potential benefit in the
treatment of various inflammatory and immune‐mediated diseases including periodontitis …

Chronic periodontitis is characterized by inflammation of periodontal tissues, leading to
bone resorption and tooth loss. The goal of treatment is to regenerate periodontal tissues …

The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …

Background The treatment of molar furcation defects remains a considerable challenge in
clinical practice. The identification of clinical measurements influential to treatment outcomes …