Neonatal treatment with lipopolysaccharide differentially affects adult anxiety responses in the light–dark test and taste neophobia test in male and female rats

CM Tenk, M Kavaliers, KP Ossenkopp - International Journal of …, 2013 - Elsevier
Neonatal administration of the bacterial cell wall component, lipopolysaccharide (LPS) has
been shown to alter a variety of behavioural and physiological processes in the adult rat …

Deletion of ovarian hormones induces a sickness behavior in rats comparable to the effect of lipopolysaccharide

H Azizi-Malekabadi, M Hosseini… - Neurology research …, 2015 - Wiley Online Library
Neuroimmune factors have been proposed as the contributors to the pathogenesis of
sickness behaviors. The effects of female gonadal hormones on both neuroinflammation …

[HTML][HTML] Discovery of nitro-azolo [1, 5-a] pyrimidines with anti-inflammatory and protective activity against LPS-induced acute lung injury

A Spasov, V Kosolapov, D Babkov, V Klochkov… - Pharmaceuticals, 2022 - mdpi.com
Acute lung injury remains a challenging clinical condition, necessitating the development of
novel, safe and efficient treatments. The prevention of macrophage M1-polarization is a …

Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism

M Shimodahira, S Fujimoto, E Mukai… - Journal of …, 2010 - joe.bioscientifica.com
Fetal intrauterine growth restriction (IUGR) is a frequently occurring and serious
complication of pregnancy. Infants exposed to IUGR are at risk for numerous perinatal …

Vanillic acid alleviates lipopolysaccharide-induced anxiety/depression-like behaviors and cerebral oxidative stress in male rats

SM Vestegani, S Hajipour, A Sarkaki, Y Farbood… - Learning and …, 2022 - Elsevier
Oxidative stress is thought to be one of the important causes of anxiety and depression.
Vanillic acid (VA) is a phenolic compound with a well-known anti-oxidative property. The …

A translational and multidisciplinary approach to studying the Garcia effect, a higher form of learning with deep evolutionary roots

V Rivi, A Batabyal, C Benatti, P Sarti… - Journal of …, 2024 - journals.biologists.com
Animals, including humans, learn and remember to avoid a novel food when its ingestion is
followed, hours later, by sickness–a phenomenon initially identified during World War II as a …

[HTML][HTML] Neuropharmacological evaluation of a novel 5-HT3 receptor antagonist (4-benzylpiperazin-1-yl)(3-methoxyquinoxalin-2-yl) methanone (6g) on …

S Bhatt, R Mahesh, T Devadoss… - Journal of Basic and …, 2017 - degruyter.com
Background: 5-HT 3 receptor antagonists play a key role in the management of psychiatric
disorders such as, depression and anxiety. They may act through modulation of serotonergic …

Why a developmental cognitive neuroscience approach may be key for future-proofing microbiota-gut-brain research

N Johnstone, KC Kadosh - Behavioral and Brain Sciences, 2019 - search.proquest.com
Here we argue that a multidisciplinary research approach, such as currently practised in the
field of developmental cognitive neuroscience, is key to maintaining current momentum and …

Beneficial effects of selenium against the behavioral consequences of lipopolysaccharide administration in rats

M Mansouri, MM Sotoudeh, A Shamshirian… - Learning and …, 2021 - Elsevier
Objective The effects of selenium on behavioral consequences of lipopolysaccharide (LPS)
injection in rats was assessed. Materials and methods The animals were randomized into …

Bodyweight, locomotion, and behavioral responses of the naked mole rat (Heterocephalus glaber) to lipopolysaccharide administration

ML Kisipan, RO Ojoo, TI Kanui… - Journal of Comparative …, 2022 - Springer
The naked mole rat has unique biologic characteristics that include atypical inflammatory
responses. Lipopolysaccharide induces inflammation which triggers brain centers …