Causal effects of exposure to ambient air pollution on cancer risk: Insights from genetic evidence

W Li, W Wang - Science of the Total Environment, 2024 - Elsevier
Air pollution has been increasingly linked to cancer risk. However, the genetic causality
between air pollution and cancer risk remains poorly understood. To elucidate the potential …

[HTML][HTML] New insights into the biology and development of lung cancer in never smokers—implications for early detection and treatment

P Wang, S Sun, S Lam, WW Lockwood - Journal of Translational Medicine, 2023 - Springer
Lung cancer is the leading cause of cancer deaths worldwide. Despite never smokers
comprising between 10 and 25% of all cases, lung cancer in never smokers (LCNS) is …

[HTML][HTML] Urban dust particles disrupt mitotic progression by dysregulating Aurora kinase B-related functions

J Ryu, SH Lee, S Kim, JW Jeong, KS Kim… - Journal of Hazardous …, 2023 - Elsevier
Particulate matter (PM), a major component of outdoor air pollution, damages DNA and
increases the risk of cancer. Although the harmful effects of PM at the genomic level are …

[HTML][HTML] Epigenetic mechanisms of particulate matter exposure: air pollution and hazards on human health

D Gavito-Covarrubias, I Ramírez-Díaz… - Frontiers in …, 2024 - frontiersin.org
Environmental pollution nowadays has not only a direct correlation with human health
changes but a direct social impact. Epidemiological studies have evidenced the increased …

Particulate matter pollution, polygenic risk score and mosaic loss of chromosome Y in middle-aged and older men from the Dongfeng-Tongji cohort study

X Guan, X Meng, G Zhong, Z Zhang, C Wang… - Journal of Hazardous …, 2024 - Elsevier
Mosaic loss of chromosome Y (mLOY) is the most common somatic alteration as men aging
and may reflect genome instability. PM exposure is a major health concern worldwide, but its …

Prediction of molecular-specific mutagenic alerts and related mechanisms of chemicals by a convolutional neural network (CNN) model based on SMILES split

C Chen, Z Huang, X Zou, S Li, D Zhang… - Science of The Total …, 2024 - Elsevier
Structural alerts (SAs) are essential to identify chemicals for toxicity evaluation and health
risk assessment. We constructed a novel SMILES split-based deep learning model (SSDL) …

Air pollution and cancer daily mortality in Hangzhou, China: an ecological research

Z Cheng, K Qin, Y Zhang, Z Yu, B Li, C Jiang, J Xu - BMJ open, 2024 - bmjopen.bmj.com
Background Long-term exposure to air pollution has been linked to cancer incidence.
However, the evidence is limited regarding the effect of short-term exposure to air pollution …