[HTML][HTML] Milk fatty acid profiles in different animal species: Focus on the potential effect of selected pufas on metabolism and brain functions

MP Mollica, G Trinchese, F Cimmino, E Penna… - Nutrients, 2021 - mdpi.com
Milk contains several important nutrients that are beneficial for human health. This review
considers the nutritional qualities of essential fatty acids (FAs), especially omega-3 (ω-3) …

[HTML][HTML] Interneuron dysfunction and inhibitory deficits in autism and fragile X syndrome

T Nomura - Cells, 2021 - mdpi.com
The alteration of excitatory–inhibitory (E–I) balance has been implicated in various
neurological and psychiatric diseases, including autism spectrum disorder (ASD). Fragile X …

Cognitive-affective functions of the cerebellum

S Rudolph, A Badura, S Lutzu, SS Pathak… - Journal of …, 2023 - Soc Neuroscience
The cerebellum, traditionally associated with motor coordination and balance, also plays a
crucial role in various aspects of higher-order function and dysfunction. Emerging research …

[HTML][HTML] The little brain and the seahorse: Cerebellar-hippocampal interactions

JM Froula, SD Hastings… - Frontiers in Systems …, 2023 - frontiersin.org
There is a growing appreciation for the cerebellum beyond its role in motor function and
accumulating evidence that the cerebellum and hippocampus interact across a range of …

[HTML][HTML] Chemogenetics as a neuromodulatory approach to treating neuropsychiatric diseases and disorders

J Song, RV Patel, M Sharif, A Ashokan, M Michaelides - Molecular Therapy, 2022 - cell.com
Chemogenetics enables precise, non-invasive, and reversible modulation of neural activity
via the activation of engineered receptors that are pharmacologically selective to …

Cerebellar dysfunction in autism spectrum disorders: deriving mechanistic insights from an internal model framework

E Kelly, CO Escamilla, PT Tsai - Neuroscience, 2021 - Elsevier
Autism spectrum disorders (ASD) are highly prevalent neurodevelopmental disorders;
however, the neurobiological mechanisms underlying disordered behavior in ASD remain …

[HTML][HTML] Social memory deficit caused by dysregulation of the cerebellar vermis

OY Chao, SS Pathak, H Zhang, GJ Augustine… - Nature …, 2023 - nature.com
Social recognition memory (SRM) is a key determinant of social interactions. While the
cerebellum emerges as an important region for social behavior, how cerebellar activity …

Functional convergence of motor and social processes in lobule IV/V of the mouse cerebellum

OY Chao, H Zhang, SS Pathak, JP Huston, YM Yang - The Cerebellum, 2021 - Springer
Topographic organization of the cerebellum is largely segregated into the anterior and
posterior lobes that represent its “motor” and “non-motor” functions, respectively. Although …

[HTML][HTML] Impact of cerebellar-specific genetic and circuit manipulations on the behavioral phenotype and cerebellar physiology in murine autism models

L Wahl, I Serra, A Badura - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights•Stereotyped behavior has large variability within cerebellar-specific genetic
models.•Cerebellar manipulations show region-specific and time-dependent effects on …

[HTML][HTML] Understanding the relationship between cerebellar structure and social abilities

Y Elandaloussi, DL Floris, P Coupé, E Duchesnay… - Molecular autism, 2023 - Springer
Background The cerebellum contains more than 50% of all neurons in the brain and is
involved in a broad range of cognitive functions, including social communication and social …