[HTML][HTML] Targeting inflammation in atherosclerosis—from experimental insights to the clinic

O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options

TJ Guzik, SA Mohiddin, A Dimarco, V Patel… - Cardiovascular …, 2020 - academic.oup.com
The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents
the greatest medical challenge in decades. We provide a comprehensive review of the …

[HTML][HTML] Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study

I Katsoularis, O Fonseca-Rodríguez, P Farrington… - The Lancet, 2021 - thelancet.com
Background COVID-19 is a complex disease targeting many organs. Previous studies
highlight COVID-19 as a probable risk factor for acute cardiovascular complications. We …

Association between gout flare and subsequent cardiovascular events among patients with gout

E Cipolletta, LJ Tata, G Nakafero, AJ Avery, MA Mamas… - Jama, 2022 - jamanetwork.com
Importance Gout is associated with cardiovascular diseases. The temporal association
between gout flares and cardiovascular events has not been investigated. Objective To …

[HTML][HTML] Organ-specific manifestations of COVID-19 infection

M Gavriatopoulou, E Korompoki, D Fotiou… - Clinical and …, 2020 - Springer
Although COVID-19 presents primarily as a lower respiratory tract infection transmitted via
air droplets, increasing data suggest multiorgan involvement in patients that are infected …

[HTML][HTML] Defining trained immunity and its role in health and disease

MG Netea, J Domínguez-Andrés, LB Barreiro… - Nature Reviews …, 2020 - nature.com
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers …

Cardiac Troponin for Assessment of Myocardial Injury in COVID-19: JACC Review Topic of the Week

Y Sandoval, JL Januzzi Jr, AS Jaffe - Journal of the American college of …, 2020 - jacc.org
Increases in cardiac troponin indicative of myocardial injury are common in patients with
coronavirus disease-2019 (COVID-19) and are associated with adverse outcomes such as …

COVID-19 and cardiac injury: clinical manifestations, biomarkers, mechanisms, diagnosis, treatment, and follow up

A Tajbakhsh, SM Gheibi Hayat… - Expert review of anti …, 2021 - Taylor & Francis
ABSTRACT Introduction Coronavirus disease 2019 (COVID-19) has the characteristics of
high transmission, diverse clinical manifestations, and a long incubation period. In addition …

Azithromycin in the treatment of COVID-19: a review

D Echeverría-Esnal, C Martin-Ontiyuelo… - Expert review of anti …, 2021 - Taylor & Francis
Introduction SARS-CoV-2 is a novel virus that causes coronavirus disease-19 (COVID-19).
Antiviral and immunomodulatory agents have been proposed as potential treatments …

Neutrophils as regulators of cardiovascular inflammation

C Silvestre-Roig, Q Braster, A Ortega-Gomez… - Nature Reviews …, 2020 - nature.com
Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular
disease. However, studies in the past decade have demonstrated the important functions of …