Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection

L Lan, TS Murray, BI Kazmierczak… - Molecular …, 2010 - Wiley Online Library
Oxidative stress is one of the main challenges bacteria must cope with during infection.
Here, we identify a new oxidative stress sensing and response ospR (o xidative s tress …

Temperate Bacteriophages (Prophages) in Pseudomonas aeruginosa Isolates Belonging to the International Cystic Fibrosis Clone (CC274)

A Ambroa, L Blasco, C López-Causapé… - Frontiers in …, 2020 - frontiersin.org
Bacteriophages are important in bacterial ecology and evolution. Pseudomonas aeruginosa
is the most prevalent bacterial pathogen in chronic bronchopulmonary infection in cystic …

The MexJK Multidrug Efflux Pump Is Not Involved in Acquired or Intrinsic Antibiotic Resistance in Pseudomonas aeruginosa, but Modulates the Bacterial Quorum …

R Amieva, T Gil-Gil, JL Martínez… - International Journal of …, 2022 - mdpi.com
Multidrug efflux pumps are critical elements in both intrinsic and acquired antibiotic
resistance of bacterial populations. Consequently, most studies regarding these protein …

[HTML][HTML] Increasing resistance of the Liverpool epidemic strain (LES) of Pseudomonas aeruginosa (Psa) to antibiotics in cystic fibrosis (CF)—a cause for concern?

A Ashish, M Shaw, C Winstanley, MJ Ledson… - Journal of cystic …, 2012 - Elsevier
BACKGROUND: Transmissible Pseudomonas aeruginosa (Psa) strains such as the
Liverpool Epidemic Strain (LES) are now widespread throughout UK CF clinics: their …

Fatty acid biosynthesis in Pseudomonas aeruginosa is initiated by the FabY class of β-ketoacyl acyl carrier protein synthases

Y Yuan, M Sachdeva, JA Leeds… - Journal of …, 2012 - Am Soc Microbiol
The prototypical type II fatty acid synthesis (FAS) pathway in bacteria utilizes two distinct
classes of β-ketoacyl synthase (KAS) domains to assemble long-chain fatty acids, the KASIII …

Evaluating the Antivirulence Effects of New Thiazolidinedione Compounds Against Pseudomonas aeruginosa PAO1

N Shakour, E Taheri, F Rajabian, S Tarighi… - Microbial Drug …, 2022 - liebertpub.com
Pseudomonas aeruginosa is an opportunistic pathogen that causes several serious health
problems and numerous forms of virulence. During the treatment of P. aeruginosa infections …

Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Infection in an Ex Vivo Pig Model of the Cystic Fibrosis Lung

NE Harrington, JL Littler, F Harrison - Applied and Environmental …, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa is the predominant cause of chronic biofilm infections that form in
the lungs of people with cystic fibrosis (CF). These infections are highly resistant to …

Novel therapeutic strategies to counter Pseudomonas aeruginosa infections

JL Fothergill, C Winstanley… - Expert review of anti …, 2012 - Taylor & Francis
Pseudomonas aeruginosa is a highly successful opportunistic pathogen that displays
intrinsic multidrug resistance and has a tremendous capacity to acquire further resistance …

[HTML][HTML] Inhibition of quorum sensing regulated virulence factors and biofilm formation by eucalyptus globulus against multidrug-resistant Pseudomonas aeruginosa

PK Sagar, P Sharma, R Singh - Journal of Pharmacopuncture, 2022 - ncbi.nlm.nih.gov
Objectives The quorum-sensing–inhibitory and anti-biofilm activities of the methanol extract
of E. globulus leaves were determined against clinically isolated multidrug-resistant …

Pseudomonas aeruginosa Las quorum sensing autoinducer suppresses growth and biofilm production in Legionella species

S Kimura, K Tateda, Y Ishii, M Horikawa… - …, 2009 - microbiologyresearch.org
Bacteria commonly communicate with each other by a cell-to-cell signalling mechanism
known as quorum sensing (QS). Recent studies have shown that the Las QS autoinducer N …