Objective To compare the efficacy, safety, and cost effectiveness of direct acting oral
anticoagulants (DOACs) for patients with atrial fibrillation. Design Systematic review …

BACKGROUND: Warfarin is effective for stroke prevention in atrial fibrillation (AF), but
anticoagulation is underused in clinical care. The risk of venous thromboembolic disease …

BACKGROUND: Atrial fibrillation (AF) is a common cardiac arrhythmia that increases the risk
of thromboembolic events. Anticoagulation therapy to prevent AF-related stroke has been …

Objective To examine the comparative efficacy and safety of antithrombotic treatments
(apixaban, dabigatran, edoxaban, rivaroxaban and vitamin K antagonists (VKA) at a …

ABSTRACT Introduction: Direct oral anticoagulants (DOACs) may be regarded as some of
the most successful innovations in recent times. These drugs which were specifically …

Objective To conduct a systematic review of economic models of newer anticoagulants for
stroke prevention in atrial fibrillation (SPAF). Patients and Methods We searched Medline …

The oral anticoagulant therapy is used for the cure and the prevention of thromboembolic
diseases. In the last fifty years the warfarin has been considered the oral anticoagulant of …

Objectives To critically appraise published network meta-analyses (NMAs) evaluating the
efficacy or safety of the new oral anticogulants (NOACs) dabigatran, rivaroxaban, and …

Objective Lack of patient knowledge has been associated with poor anticoagulation control,
but the effect of patient education on clinical outcomes is unclear. We systematically …

Vitamin K antagonists (VKAs) remain as the most prescribed drug for treatment and
prevention of thrombotic disorders in many countries, despite the recent approval of the new …