Interventional therapies for acute pulmonary embolism: current status and principles for the development of novel evidence: a scientific statement from the American …

J Giri, AK Sista, I Weinberg, C Kearon, DJ Kumbhani… - Circulation, 2019 - Am Heart Assoc
Pulmonary embolism (PE) represents the third leading cause of cardiovascular mortality.
The technological landscape for management of acute intermediate-and high-risk PE is …

Persistent right ventricular dysfunction, functional capacity limitation, exercise intolerance, and quality of life impairment following pulmonary embolism: systematic …

AK Sista, LE Miller, SR Kahn, JA Kline - Vascular Medicine, 2017 - journals.sagepub.com
Long-term right ventricular (RV) function, functional capacity, exercise capacity, and quality
of life following pulmonary embolism (PE), and the impact of thrombolysis, are unclear. A …

Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism

N Kucher, P Boekstegers, OJ Müller, C Kupatt… - Circulation, 2014 - Am Heart Assoc
Background—In patients with acute pulmonary embolism, systemic thrombolysis improves
right ventricular (RV) dilatation, is associated with major bleeding, and is withheld in many …

Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific …

MR Jaff, MS McMurtry, SL Archer, M Cushman… - Circulation, 2011 - Am Heart Assoc
Methods A writing group was established with representation from the Council on Peripheral
Vascular Disease and Council on Cardiopulmonary, Critical Care, Perioperative and …

Moderate pulmonary embolism treated with thrombolysis (from the “MOPETT” Trial)

M Sharifi, C Bay, L Skrocki, F Rahimi… - The American journal of …, 2013 - Elsevier
The role of low-dose thrombolysis in the reduction of pulmonary artery pressure in moderate
pulmonary embolism (PE) has not been investigated. Because the lungs are very sensitive …

[HTML][HTML] Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism

S Konstantinides, A Geibel, G Heusel… - … England Journal of …, 2002 - Mass Medical Soc
Background The use of thrombolytic agents in the treatment of hemodynamically stable
patients with acute submassive pulmonary embolism remains controversial. Methods We …

[HTML][HTML] Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at 3 months: multicenter double‐blind, placebo …

JA Kline, KE Nordenholz, DM Courtney… - Journal of thrombosis …, 2014 - Elsevier
Background Acute pulmonary embolism (PE) can worsen quality of life due to persistent
dyspnea or exercise intolerance. Objective Test if tenecteplase increases the probability of a …

Thrombolysis compared with heparin for the initial treatment of pulmonary embolism: a meta-analysis of the randomized controlled trials

S Wan, DJ Quinlan, G Agnelli, JW Eikelboom - Circulation, 2004 - Am Heart Assoc
Background—Randomized trials and meta-analyses have reached conflicting conclusions
about the role of thrombolytic therapy for the treatment of acute pulmonary embolism …

Late outcomes of pulmonary embolism: the post-PE syndrome

AK Sista, FA Klok - Thrombosis research, 2018 - Elsevier
Abstract The post-Pulmonary Embolism (post-PE) syndrome is being increasingly
recognized as a long-term consequence of PE. Its most severe manifestation, chronic …

Prospective evaluation of right ventricular function and functional status 6 months after acute submassive pulmonary embolism: frequency of persistent or subsequent …

JA Kline, MT Steuerwald, MR Marchick… - Chest, 2009 - Elsevier
Background No published data have systematically documented pulmonary artery pressure
over an intermediate time period after submassive pulmonary embolism (PE). The aim of this …