Effects and mechanisms of curcumin for the prevention and management of cancers: An updated review
ZJ Yang, SY Huang, DD Zhou, RG Xiong, CN Zhao… - Antioxidants, 2022 - mdpi.com
Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …
Hexokinase 2 in cancer: a prima donna playing multiple characters
Hexokinases are a family of ubiquitous exose-phosphorylating enzymes that prime glucose
for intracellular utilization. Hexokinase 2 (HK2) is the most active isozyme of the family …
for intracellular utilization. Hexokinase 2 (HK2) is the most active isozyme of the family …
Tumor metastasis: Mechanistic insights and therapeutic interventions
M Liu, J Yang, B Xu, X Zhang - MedComm, 2021 - Wiley Online Library
Cancer metastasis is responsible for the vast majority of cancer‐related deaths worldwide. In
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …
Enhancement of anti-PD-1/PD-L1 immunotherapy for osteosarcoma using an intelligent autophagy-controlling metal organic framework
YX Ge, TW Zhang, L Zhou, W Ding, HF Liang, ZC Hu… - Biomaterials, 2022 - Elsevier
Poor immunogenicity and compromised T cell infiltration impede the application of immune-
checkpoint blockade (ICB) immunotherapy for osteosarcoma (OS). Although autophagy is …
checkpoint blockade (ICB) immunotherapy for osteosarcoma (OS). Although autophagy is …
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes
W Zheng, Q Chen, H Liu, L Zeng, Y Zhou, X Liu, Y Bai… - Autophagy, 2023 - Taylor & Francis
Glioblastoma multiforme (GBM) is the most common brain malignancy insensitive to
radiotherapy (RT). Although macroautophagy/autophagy was reported to be a fundamental …
radiotherapy (RT). Although macroautophagy/autophagy was reported to be a fundamental …
Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response
M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
[HTML][HTML] SDC1-TGM2-FLOT1-BHMT complex determines radiosensitivity of glioblastoma by influencing the fusion of autophagosomes with lysosomes
L Zeng, W Zheng, X Liu, Y Zhou, X Jin, Y Xiao, Y Bai… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Glioblastoma (GBM) is the most common and malignant primary brain tumor in
adults. Radiotherapy has long been an important treatment for GBM. Despite recent …
adults. Radiotherapy has long been an important treatment for GBM. Despite recent …
Autophagy-related long non-coding RNA is a prognostic indicator for bladder cancer
J Wan, C Guo, H Fang, Z Xu, Y Hu, Y Luo - Frontiers in oncology, 2021 - frontiersin.org
Bladder cancer (BC) is one of the most common malignant urinary system tumors, and its
prognosis is poor. In recent years, autophagy has been closely linked to the development of …
prognosis is poor. In recent years, autophagy has been closely linked to the development of …
[HTML][HTML] Harnessing G-quadruplex ligands for lung cancer treatment: a comprehensive overview
J Figueiredo, M Djavaheri-Mergny, L Ferret… - Drug Discovery …, 2023 - Elsevier
Lung cancer (LC) remains a leading cause of mortality worldwide, and new therapeutic
strategies are urgently needed. One such approach revolves around the utilization of four …
strategies are urgently needed. One such approach revolves around the utilization of four …
Nanomedicines for overcoming cancer drug resistance
T Hu, H Gong, J Xu, Y Huang, F Wu, Z He - Pharmaceutics, 2022 - mdpi.com
Clinically, cancer drug resistance to chemotherapy, targeted therapy or immunotherapy
remains the main impediment towards curative cancer therapy, which leads directly to …
remains the main impediment towards curative cancer therapy, which leads directly to …