Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …

Hexokinases are a family of ubiquitous exose-phosphorylating enzymes that prime glucose
for intracellular utilization. Hexokinase 2 (HK2) is the most active isozyme of the family …

Cancer metastasis is responsible for the vast majority of cancer‐related deaths worldwide. In
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …

Poor immunogenicity and compromised T cell infiltration impede the application of immune-
checkpoint blockade (ICB) immunotherapy for osteosarcoma (OS). Although autophagy is …

Glioblastoma multiforme (GBM) is the most common brain malignancy insensitive to
radiotherapy (RT). Although macroautophagy/autophagy was reported to be a fundamental …

Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

Rationale: Glioblastoma (GBM) is the most common and malignant primary brain tumor in
adults. Radiotherapy has long been an important treatment for GBM. Despite recent …

Bladder cancer (BC) is one of the most common malignant urinary system tumors, and its
prognosis is poor. In recent years, autophagy has been closely linked to the development of …

Lung cancer (LC) remains a leading cause of mortality worldwide, and new therapeutic
strategies are urgently needed. One such approach revolves around the utilization of four …

Clinically, cancer drug resistance to chemotherapy, targeted therapy or immunotherapy
remains the main impediment towards curative cancer therapy, which leads directly to …