Antisense technology is now beginning to deliver on its promise to treat diseases by
targeting RNA. Nine single-stranded antisense oligonucleotide (ASO) drugs representing …

Statins are a class of widely prescribed drugs used to reduce low-density lipoprotein
cholesterol (LDL-C) and important to prevent cardiovascular diseases (CVD). Most statin …

Alzheimer's disease (AD), the most common cause of dementia, is a complex and
multifactorial disease involving genetic and environmental factors, with …

Background Inclisiran is a small interfering RNA molecule that reduces low-density
lipoprotein cholesterol (LDL-C) by inhibition of proprotein convertase subtilisin/kexin type 9 …

BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

The objective of this scientific statement is to evaluate contemporary evidence that either
supports or refutes the conclusion that aggressive low-density lipoprotein cholesterol …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, a new cholesterol-lowering
strategy, can decrease low-density lipoprotein cholesterol (LDL-C) levels by inhibiting …

There have been many meta-analyses for statins, ezetimibe and proprotein convertase
subtilisin/kexin type 9 inhibitors (PCSK9i) to evaluate clinical outcomes, but the efficacy and …

Objective We aimed to investigate the relationship between preoperative lipid level and
postoperative delirium (POD) and explore whether lipid's effect on POD is mediated by POD …

Acute ischemic stroke (AIS) represents an important cause of disability and death. Since
only a minor percentage of patients with AIS are eligible for acute therapy, the management …