Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …

Alzheimer's disease (AD) is the primary cause of dementia and is anticipated to impose a
substantial economic burden in the future. Over a significant period, the widely accepted …

Emerging evidence indicates that vascular stress is an important contributor to the
pathophysiology of Alzheimer's disease and related dementias (ADRD). Hydrogen sulfide …

Background and Objectives Rates of cerebrovascular disease increase after menopause,
which is often attributed to the absence of hormones. It remains unknown whether the …

Patients with Alzheimer's disease (AD) often present with imaging features indicative of
small-vessel injury, among which, white-matter hyperintensities (WMHs) are the most …

Co-occurrence of beta amyloid (Aβ) and white matter hyperintensities (WMHs) increase the
risk of dementia and both are considered biomarkers of preclinical dementia. Moderation …

Abstract Background White matter hyperintensities (WMHs) are often measured globally, but
spatial patterns of WMHs could underlie different risk factors and neuropathological and …

In older adults without dementia, White Matter Hyperintensities (WMH) in MRI have been
shown to be highly associated with cerebral amyloid deposition, measured by the Pittsburgh …

INTRODUCTION Amyloidosis, including cerebral amyloid angiopathy, and markers of small
vessel disease (SVD) vary across dominantly inherited Alzheimer's disease (DIAD) …

INTRODUCTION We assessed whether co‐morbid small vessel disease (SVD) has clinical
predictive value in preclinical or prodromal Alzheimer's disease. METHODS In 1090 non …