Vascular inflammation is associated with and in large part driven by changes in the
leukocyte compartment of the vessel wall. Here, we focus on monocyte influx during …

A more nuanced approach to drug design is to use multiple drugs in combination to target
interacting or complementary pathways. Drug combination treatments have shown higher …

Heatmapper is a freely available web server that allows users to interactively visualize their
data in the form of heat maps through an easy-to-use graphical interface. Unlike existing non …

Atherosclerosis is the disease process that underlies heart attack and stroke. Advanced
lesions at risk of rupture are characterized by the pathological accumulation of diseased …

Cytoscape is a free software package for visualizing, modeling and analyzing molecular and
genetic interaction networks. This protocol explains how to use Cytoscape to analyze the …

Heterogeneity of embryological origins is a hallmark of vascular smooth muscle cells
(SMCs) and may influence the development of vascular disease. Differentiation of human …

Late embryogenesis abundant (LEA) proteins are hydrophilic, mostly intrinsically disordered
proteins, which play major roles in desiccation tolerance. In Arabidopsis thaliana, 51 genes …

Poly (A) tails are 3′ modifications of eukaryotic mRNAs that are important in the control of
translation and mRNA stability. We identified hundreds of mouse liver mRNAs that exhibit …

Genetic variation at the chromosome 9p21 risk locus promotes cardiovascular disease;
however, it is unclear how or which proteins encoded at this locus contribute to disease. We …

Objective—Comparison of gene expression in stable versus unstable atherosclerotic plaque
may be confounded by interpatient variability. The aim of this study was to identify …