mTOR signaling: new insights into cancer, cardiovascular diseases, diabetes and aging
The mechanistic/mammalian target of rapamycin (mTOR), a member of the phosphoinositide
3-kinase (PI3K) related kinase family, integrates intracellular and environmental cues that …
3-kinase (PI3K) related kinase family, integrates intracellular and environmental cues that …
Integrated Analysis of lncRNA–miRNA–mRNA Regulatory Network in Rapamycin-Induced Cardioprotection against Ischemia/Reperfusion Injury in Diabetic Rabbits
The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides
protection against myocardial ischemia/reperfusion (I/R) injury in diabetes. Since …
protection against myocardial ischemia/reperfusion (I/R) injury in diabetes. Since …
Immunolocalization of Matrix Metalloproteinases 2 and 9 and Their Inhibitors in the Hearts of Rats Treated with Immunosuppressive Drugs—An Artificial Intelligence …
A Wilk, M Król, K Kiełbowski, E Bakinowska… - Biomedicines, 2024 - mdpi.com
Background: Immunosuppressive agents represent a broad group of drugs, such as
calcineurin inhibitors, mTOR inhibitors, and glucocorticosteroids, among others. These …
calcineurin inhibitors, mTOR inhibitors, and glucocorticosteroids, among others. These …
Autophagy in heart failure: Insights into mechanisms and therapeutic implications
M Bielawska, M Warszyńska, M Stefańska… - Journal of …, 2023 - mdpi.com
Autophagy, a dynamic and complex process responsible for the clearance of damaged
cellular components, plays a crucial role in maintaining myocardial homeostasis. In the …
cellular components, plays a crucial role in maintaining myocardial homeostasis. In the …