Since the 1960 s, our health has been compromised by exposure to over 350,000 newly
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …

The epithelial barrier theory links the recent rise in chronic non-communicable diseases,
notably autoimmune and allergic disorders, to environmental agents disrupting the epithelial …

In vitro organ models allow for the creation of precise preclinical models that mimic organ
physiology. During a pandemic of a life-threatening acute respiratory disease, an improved …

Chronic inflammatory conditions including allergic, autoimmune, metabolic, and
neuropsychiatric disorders are constantly increasing and leading to a high burden …

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by type 2
cytokine-driven skin inflammation and epithelial barrier dysfunction. The latter is believed to …

Cow's milk protein allergy (CMPA) is the most common food allergy (FA) in infancy, affecting
approximately 2% of children under 4 years of age. According to recent studies, the …

Chronic exposure to harmful pollutants, chemicals, and pathogens from the environment can
lead to pathological changes in the epithelial barrier, which increase the risk of developing …

Atopic diseases, which currently affect around one billion people worldwide, are
experiencing a rising prevalence [1, 2]. Atopic diseases are characterized by intricate …

Background: Early phase clinical research provided initial support for the use of a
multispecies probiotic supplement to improve quality of life (QoL) in adults with seasonal …

Introduction Up to 90% of asthmatic patients have comorbid allergic rhinitis (AR). Although
appropriate therapy of AR can improve asthma symptoms and management, AR is often …