Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Cues for seizure timing

VR Rao, MG Leguia, TK Tcheng, MO Baud - Epilepsia, 2021 - Wiley Online Library
The cyclical organization of seizures in epilepsy has been described since antiquity.
However, historical explanations for seizure cycles—based on celestial, hormonal, and …

Seizure cycles in focal epilepsy

MG Leguia, RG Andrzejak, C Rummel, JM Fan… - JAMA …, 2021 - jamanetwork.com
Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …

[HTML][HTML] Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat

L Sterrenburg, B Gaszner, J Boerrigter, L Santbergen… - PloS one, 2011 - journals.plos.org
Background Although the higher prevalence of depression in women than in men is well
known, the neuronal basis of this sex difference is largely elusive. Methods Male and female …

[HTML][HTML] Application of Spectral Methods of Analysis for Description of Ultradian Biorhythms at the Levels of Physiological Systems, Cells and Molecules

ME Astashev, DA Serov, SV Gudkov - Mathematics, 2023 - mdpi.com
The presence of biological rhythms is a characteristic of all living organisms. Over the past
60 years, scientists around the world have accumulated a huge amount of data on rhythmic …

[HTML][HTML] Psychosocial stress and immunity—what can we learn from pig studies?

U Gimsa, M Tuchscherer, E Kanitz - Frontiers in Behavioral …, 2018 - frontiersin.org
Psychosocial stress may impair immune functions and provoke the development of
pathologies. The underlying communication between the brain and the immune system is …

Endogenous multidien rhythm of epilepsy in rats

MO Baud, A Ghestem, JJ Benoliel, C Becker… - Experimental …, 2019 - Elsevier
Recent trials of chronic EEG in humans showed that epilepsy is a cyclical disorder of the
brain with rhythms at multiple time-scales: circadian, multi-day (multidien) or even seasonal …

Sex‐dependent and differential responses to acute restraint stress of corticotropin‐releasing factor–producing neurons in the rat paraventricular nucleus, central …

L Sterrenburg, B Gaszner, J Boerrigter… - Journal of …, 2012 - Wiley Online Library
Male and female rodents respond differently to acute stress. We tested our hypothesis that
this sex difference is based on differences in stress sensitivity of forebrain areas, by …

Higher susceptibility of somatostatin 4 receptor gene-deleted mice to chronic stress-induced behavioral and neuroendocrine alterations

B Scheich, É Borbély, I Ábrahám, V Csernus… - Neuroscience, 2017 - Elsevier
Abstract The somatostatin 4 receptor (sst 4) is widely expressed in stress-related brain areas
(eg hippocampus, amygdala) and regulates the emotional behavior in acute situations …

[HTML][HTML] Both basal and acute restraint stress-induced c-Fos expression is influenced by age in the extended amygdala and brainstem stress centers in male rats

LÁ Kovács, JA Schiessl, AE Nafz, V Csernus… - Frontiers in Aging …, 2018 - frontiersin.org
The hypothalamus-pituitary-adrenal axis (HPA) is the main regulator of the stress response.
The key of the HPA is the parvocellular paraventricular nucleus of the hypothalamus (pPVN) …