[HTML][HTML] The role of SOX family members in solid tumours and metastasis

D Grimm, J Bauer, P Wise, M Krüger… - Seminars in cancer …, 2020 - Elsevier
Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

Protein palmitoylation in cancer: molecular functions and therapeutic potential

B Zhou, Q Hao, Y Liang, E Kong - Molecular oncology, 2023 - Wiley Online Library
Protein S‐palmitoylation (hereinafter referred to as protein palmitoylation) is a reversible
lipid posttranslational modification catalyzed by the zinc finger DHHC‐type containing …

[HTML][HTML] Advances of Wnt signalling pathway in colorectal cancer

Y Zhu, X Li - Cells, 2023 - mdpi.com
Colorectal cancer (CRC) represents one of the most common cancers worldwide, with a
high mortality rate despite the decreasing incidence and new diagnostic and therapeutic …

[HTML][HTML] Blocking the Wnt/β-catenin signaling pathway to treat colorectal cancer: Strategies to improve current therapies

Y Chen, M Chen, K Deng - International journal of …, 2022 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common malignant tumor types occurring in the
digestive system. The incidence of CRC has exhibits yearly increases and the mortality rate …

Wnt pathway modulators in cancer therapeutics: An update on completed and ongoing clinical trials

A Neiheisel, M Kaur, N Ma, P Havard… - … Journal of Cancer, 2022 - Wiley Online Library
Wnt signaling plays an essential role in the initiation and progression of various types of
cancer. Besides, the Wnt pathway components have been established as reliable …

[HTML][HTML] Regulation of Wnt signaling pathways at the plasma membrane and their misregulation in cancer

Y Azbazdar, M Karabicici, E Erdal… - Frontiers in cell and …, 2021 - frontiersin.org
Wnt signaling is one of the key signaling pathways that govern numerous physiological
activities such as growth, differentiation and migration during development and …

Ginkgetin: A natural biflavone with versatile pharmacological activities

M Adnan, A Rasul, G Hussain, MA Shah… - Food and Chemical …, 2020 - Elsevier
Natural products, being richly endowed with curative powers, have become spotlight for
biomedical and pharmaceutical research to develop novel therapeutics during recent years …

Drug repurposing and relabeling for cancer therapy: Emerging benzimidazole antihelminthics with potent anticancer effects

J Nath, R Paul, SK Ghosh, J Paul, B Singha, N Debnath - Life Sciences, 2020 - Elsevier
Origin of drug and radio-refractory clones, cancer stem-like cells, and rapid angiogenesis
and metastasis are among the primary concerns that limit the efficacy of anticancer …

WNT10A, dermatology and dentistry

BJ Doolan, A Onoufriadis, P Kantaputra… - British Journal of …, 2021 - academic.oup.com
WNTs (Wingless‐related integration sites) are secreted glycoproteins that are involved in
signalling pathways critical to organ development and tissue regeneration. Of the 19 known …

[HTML][HTML] A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma

T Liu, J Hu, B Han, S Tan, W Jia, Y Xin - Cell Death & Disease, 2021 - nature.com
Drug resistance strikingly limits the therapeutic effect of temozolomide (TMZ)(a common
drug for glioma). Long non-coding RNA (lncRNA) RMRP has been found to be implicated in …