Thyroid cancer: risk-stratified management and individualized therapy

F Raue, K Frank-Raue - Clinical Cancer Research, 2016 - AACR
Thyroid cancer is the most common endocrine malignancy. Differentiated thyroid cancer
(DTC) with the two subtypes, papillary thyroid cancer (PTC) and follicular thyroid cancer …

An overview of once‐weekly glucagon‐like peptide‐1 receptor agonists—available efficacy and safety data and perspectives for the future

S Madsbad, U Kielgast, M Asmar… - Diabetes, Obesity …, 2011 - Wiley Online Library
Incretin‐based therapies, such as the injectable glucagon‐like peptide‐1 (GLP‐1) receptor
agonists and orally administered dipeptidyl peptidase‐4 (DPP‐4) inhibitors, have recently …

Calcitonin measurement in the evaluation of thyroid nodules in the United States: a cost-effectiveness and decision analysis

K Cheung, SA Roman, TS Wang… - The Journal of …, 2008 - academic.oup.com
Context: European studies have shown that the use of routine calcitonin screening for
detection of medullary thyroid cancer (MTC) in patients with thyroid nodules increases the …

Current management of medullary thyroid cancer

RS Sippel, M Kunnimalaiyaan, H Chen - The oncologist, 2008 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Evaluate a patient with a new diagnosis of medullary thyroid cancer. Use genetic testing for …

RET gene mutations (genotype and phenotype) of multiple endocrine neoplasia type 2 and familial medullary thyroid carcinoma

GW Krampitz, JA Norton - Cancer, 2014 - Wiley Online Library
The rapid technical advances in molecular biology and accelerating improvements in
genomic and proteomic diagnostics have led to increasingly personalized strategies for …

Vandetanib for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease: US Food …

K Thornton, G Kim, VE Maher, S Chattopadhyay… - Clinical Cancer …, 2012 - AACR
Abstract On April 6, 2011, the US Food and Drug Administration approved vandetanib
(Caprelsa tablets; AstraZeneca Pharmaceuticals LP) for the treatment of symptomatic or …

Medullary thyroid carcinoma: an update on imaging

SV Kushchayev, YS Kushchayeva… - Journal of thyroid …, 2019 - Wiley Online Library
Medullary thyroid carcinoma (MTC), arising from the parafollicular C cells of the thyroid,
accounts for 1–2% of thyroid cancers. MTC is frequently aggressive and metastasizes to …

Thyroid nodules and cancer management guidelines: comparisons and controversies

F Nabhan, MD Ringel - Endocrine-related cancer, 2017 - erc.bioscientifica.com
Thyroid cancer is an increasingly prevalent malignancy throughout the world. Management
guidelines for both thyroid nodules and thyroid cancer have been published and updated by …

Cabozantinib, vandetanib, pralsetinib and selpercatinib as treatment for progressed medullary thyroid cancer with a main focus on hypertension as adverse effect

L Højer Wang, M Wehland, PM Wise… - International Journal of …, 2023 - mdpi.com
This manuscript investigates cabozantinib, vandetanib, pralsetinib, and selpercatinib, four
tyrosine kinase inhibitors (TKIs), which are used to treat advanced and/or metastatic …

Clinical utility of 177Lu‐DOTATATE PRRT in somatostatin receptor‐positive metastatic medullary carcinoma of thyroid patients with assessment of efficacy, survival …

RV Parghane, C Naik, S Talole, A Desmukh… - Head & …, 2020 - Wiley Online Library
Background The primary aim of this study was to evaluate the therapeutic efficacy and
outcome of 177Lu‐DOTATATE peptide receptor radionuclide therapy (PRRT) in …