Prevention of Clostridium difficile Infection With Probiotics

CT Evans, S Johnson - Clinical Infectious Diseases, 2015 - academic.oup.com
Despite advances in the diagnosis and treatment of Clostridium difficile infection (CDI) and
prevention efforts to reduce the spread of C. difficile, CDI remains a significant challenge to …

[HTML][HTML] Identification of key taxa that favor intestinal colonization of Clostridium difficile in an adult Chinese population

S Gu, Y Chen, X Zhang, H Lu, T Lv, P Shen, L Lv… - Microbes and …, 2016 - Elsevier
Fecal microbial transplantation provides a high curative rate for recurrent Clostridium difficile
infection (CDI). However, limitations associated with FMT drive the need to identify key taxa …

The Role of Glutamate Dehydrogenase (GDH) Testing Assay in the Diagnosis of Clostridium difficile Infections: A High Sensitive Screening Test and an Essential …

JW Cheng, M Xiao, T Kudinha, ZP Xu, LY Sun, X Hou… - Plos one, 2015 - journals.plos.org
The incidence and severity of Clostridium difficile infection (CDI) in North America and
Europe has increased significantly since the 2000s. However, CDI is not widely recognized …

Prevalence and molecular subtyping of Blastocystis in patients with Clostridium difficile infection, Singapore

L Deng, H Tay, G Peng, JWJ Lee, KSW Tan - Parasites & Vectors, 2021 - Springer
Background Blastocystis is a common anaerobic colonic protist in humans with controversial
pathogenicity. Clostridium difficile (C. difficile) is the commonest cause of infectious diarrhea …

Clostridioides difficile toxin A remodels membranes and mediates DNA entry into cells to activate toll-like receptor 9 signaling

X Chen, X Yang, J de Anda, J Huang, D Li, H Xu… - Gastroenterology, 2020 - Elsevier
Background & Aims Clostridioides difficile toxin A (TcdA) activates the innate immune
response. TcdA co-purifies with DNA. Toll-like receptor 9 (TLR9) recognizes bacterial DNA …

Fecal microbiota transplantation for Clostridium difficile infection in patients with ileal pouches

N Lan, J Ashburn, B Shen - Gastroenterology report, 2017 - academic.oup.com
Background: Clostridium difficile infection (CDI) in patients with ileal pouch-anal
anastomosis (IPAA) has been increasingly recognized. The aim of this study was to evaluate …

Risk factors and clinical outcome of Clostridium difficile infection in patients with IBD: A single‐center retrospective study of 260 cases in China

YB Gu, MC Zhang, J Sun, KZ Lv… - Journal of Digestive …, 2017 - Wiley Online Library
OBJECTIVE Clostridium difficile infection (CDI) may lead to poor outcomes in patients with
inflammatory bowel disease (IBD). In this study we aimed to investigate the cumulative …

Seek and you shall find: prevalence of Clostridium difficile in Wuhan, China

J Galaydick, Y Xu, L Sun, E Landon, SG Weber… - American journal of …, 2015 - Elsevier
Highlights•We studied the prevalence of Clostridium difficile infection in Wuhan,
China.•Overall prevalence of Clostridium difficile infection in 2 large tertiary care centers was …

[HTML][HTML] High in vitro activity of fidaxomicin against Clostridium difficile isolates from a university teaching hospital in China

JW Cheng, QW Yang, M Xiao, SY Yu, ML Zhou… - Journal of microbiology …, 2018 - Elsevier
Background Clostridium difficile infection (CDI) is a significant cause of morbidity and
mortality in both the acute care setting and the wider healthcare system. The purpose of this …

Compositions and methods

NB Afeyan, MJL McKenzie, KD Litcofsky… - US Patent …, 2021 - Google Patents
2014-03-31 Assigned to Seres Health, Inc. reassignment Seres Health, Inc. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: GOODMAN …